์ด ์„ธ์…˜์— ๋Œ€ํ•œ ๊ธฐ๋ณธ ์„ค์ •์ด ์—…๋ฐ์ดํŠธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๊ณ ๊ฐ๋‹˜์˜ ๊ณ„์ • ์„ค์ •์„ ์˜๊ตฌ์ ์œผ๋กœ ๋ณ€๊ฒฝํ•˜๋ ค๋ฉด ๋‚ด ๊ณ„์ •์œผ๋กœ ์ด๋™ํ•˜์„ธ์š”.
์›ํ•˜๋Š” ์ˆ˜๋ น ๊ตญ๊ฐ€ ๋˜๋Š” ์‚ฌ์šฉ ์–ธ์–ด๋ฅผ ๋‚ด ๊ณ„์ •์—์„œ ์–ธ์ œ๋“ ์ง€ ์—…๋ฐ์ดํŠธํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.
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๋‡Œ์„ธํฌ๋Š” ์‹ ์ฒด์—์„œ ๊ฐ€์žฅ ๋ณต์žกํ•˜๊ณ  ์ˆ˜๋ช…์ด ๊ธธ๋ฉฐ ์˜์–‘์†Œ๊ฐ€ ๋งŽ์ด ํ•„์š”ํ•œ ์„ธํฌ์ž…๋‹ˆ๋‹ค. ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ์ง€๋Šฅ, ๊ธฐ์–ต๋ ฅ, ํ–‰๋™, ์ง‘์ค‘๋ ฅ์€ ๋‡Œ์— ๊ณต๊ธ‰๋˜๋Š” ์˜์–‘์†Œ์˜ ์˜ํ–ฅ์„ ๋ฐ›์Šต๋‹ˆ๋‹ค. ๋‚˜์ด์— ์ƒ๊ด€์—†์ด ์˜์–‘ ์ƒํƒœ๋Š” ์‚ฌ๊ณ ๋ ฅ ๋ฐ ์‹ ์ฒด ๊ธฐ๋Šฅ์„ ์œ ์ง€ํ•˜๋Š” ๋ฐ ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค.

์ด ๊ธ€์—์„œ๋Š” ๋‹ค์–‘ํ•œ ์—ฐ๋ น๋Œ€์˜ ์‚ฌ๋žŒ์ด ์ง‘์ค‘๋ ฅ๊ณผ ์ฃผ์˜๋ ฅ์„ ํšจ๊ณผ์ ์œผ๋กœ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๋ฐ ํฐ ๋„์›€์ด ๋˜๋Š” ์ฃผ์š” ๋ณด์ถฉ์ œ๋ฅผ ์„ค๋ช…ํ•ฉ๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ๋ณด์ถฉ์ œ๋Š” ์ •์‹ ์  ํ”ผ๋กœ๋ฅผ ์–ต์ œํ•˜๋Š” ๋ฐ๋„ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค.

ํ•ญ์ƒ ๊ธฐ์ดˆ ์˜์–‘์†Œ๋ถ€ํ„ฐ ๋จผ์ € ์ฑ™๊ธฐ์‹ญ์‹œ์˜ค

์šฐ์„  ์ „๋ฐ˜์ ์ธ ๊ฑด๊ฐ•๊ณผ ๋‡Œ ๊ฑด๊ฐ•์„ ๋•๋Š” ๊ธฐ๋ณธ์ ์ธ ์˜์–‘์†Œ์™€ ๋ณด์ถฉ์ œ๋ฅผ ๊ณ ๋ คํ•ด์•ผ ํ•ฉ๋‹ˆ๋‹ค. 

์ด๋Ÿฌํ•œ ๊ธฐ๋ณธ์ ์ธ ๋ณด์ถฉ์ œ๋Š” ์„ธํฌ ๋‚ด ์—๋„ˆ์ง€ ๊ณต์žฅ์ธ ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„์— ์˜ํ•œ ์—๋„ˆ์ง€ ์ƒ์„ฑ, ๊ฑด๊ฐ•ํ•œ ์„ธํฌ๋ง‰ ์œ ์ง€ ๋“ฑ์„ ๋น„๋กฏํ•œ ๋‡Œ์„ธํฌ์˜ ๋‹ค์–‘ํ•œ ๊ธฐ๋ณธ ๊ธฐ๋Šฅ์„ ๋•์Šต๋‹ˆ๋‹ค. 

์ด๋Ÿฌํ•œ ๊ธฐ๋ณธ์ ์ธ ์˜์–‘์†Œ์™€ ๋ณด์ถฉ์ œ์˜ ์ค‘์š”์„ฑ์€ ์•„๋ฌด๋ฆฌ ๊ฐ•์กฐํ•ด๋„ ์ง€๋‚˜์น˜์ง€ ์•Š์Šต๋‹ˆ๋‹ค. ๋‡Œ๊ฐ€ ์ตœ์ƒ์˜ ๊ธฐ๋Šฅ์„ ๋ฐœํœ˜ํ•˜๋ ค๋ฉด ์ด๋Ÿฌํ•œ ์˜์–‘์†Œ๊ฐ€ ์กฐํ™”๋กญ๊ฒŒ ๊ณต๊ธ‰๋˜์–ด์•ผ ํ•ฉ๋‹ˆ๋‹ค.

1. ์ข…ํ•ฉ๋น„ํƒ€๋ฏผ 

์ข…ํ•ฉ๋น„ํƒ€๋ฏผ์€ ํ‹ฐ์•„๋ฏผ(Thiamin), ๋‚˜์ด์•„์‹ (Niacin), ๋น„ํƒ€๋ฏผB6, ๋น„ํƒ€๋ฏผB12, ๊ตฌ๋ฆฌ, ์š”์˜ค๋“œ, ์ฒ ๋ถ„, ๋งˆ๊ทธ๋„ค์Š˜, ๋ง๊ฐ„, ์นผ๋ฅจ, ์•„์—ฐ์„ ๋น„๋กฏํ•ด ๋‡Œ ๋ฐ ์‹ ๊ฒฝ๊ณ„ ๊ธฐ๋Šฅ์— ํ•„์ˆ˜์ ์ธ ์˜์–‘์†Œ๋ฅผ ๊ณต๊ธ‰ํ•ฉ๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ํ•„์ˆ˜ ์˜์–‘์†Œ๊ฐ€ ๊ฒฐํ•๋˜๋ฉด ์—๋„ˆ์ง€ ์ƒ์„ฑ ๊ณผ์ •์— ๋ฌธ์ œ๊ฐ€ ์ƒ๊ฒจ ๋‡Œ์™€ ์‹ ๊ฒฝ๊ณ„ ๊ธฐ๋Šฅ์ด ์ €ํ•˜๋ฉ๋‹ˆ๋‹ค.

2. ํ”ผ์‰ฌ ์˜ค์ผ 

ํ”ผ์‰ฌ ์˜ค์ผ์€ EPA, DHA์™€ ๊ฐ™์€ ์˜ค๋ฉ”๊ฐ€3 ์ง€๋ฐฉ์‚ฐ์ด ํ’๋ถ€ํ•ฉ๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ์ง€๋ฐฉ์‚ฐ์€ ์—ฐ๋ น๋Œ€์™€ ์ƒ๊ด€์—†์ด ๋ชจ๋“  ์‚ฌ๋žŒ์˜ ๋‡Œ ๊ธฐ๋Šฅ์— ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. ํŠนํžˆ ๋‡Œ์˜ ์ค‘์š”ํ•œ ๊ตฌ์„ฑ์š”์†Œ์ธ ์ง€๋ฐฉ์‚ฐ ๋†๋„๋ฅผ ์ ์ ˆํžˆ ์œ ์ง€ํ•˜๋Š” ๊ฒƒ์€ ์„ฑ์žฅ๊ธฐ์˜ ๋‡Œ๊ฐ€ ์ •์ƒ์ ์œผ๋กœ ๋ฐœ๋‹ฌํ•˜๋Š” ๋ฐ ํฐ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ์ˆ˜๋งŽ์€ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด EPA, DHA ๊ฐ™์€ ์˜ค๋ฉ”๊ฐ€3 ์ง€๋ฐฉ์‚ฐ ๋ณด์ถฉ์ œ๋Š” ์–ด๋ฆฐ์ด์™€ ์„ฑ์ธ์˜ ๋‡Œ ๊ฑด๊ฐ•์— ์ค‘๋Œ€ํ•œ ์˜ํ–ฅ์„ ๋ฏธ์น  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. EPA์™€ DHA์˜ ํ•˜๋ฃจ ๊ถŒ์žฅ ์„ญ์ทจ๋Ÿ‰์€ ์–ด๋ฆฐ์ด์˜ ๊ฒฝ์šฐ 600-1,000mg, ์„ฑ์ธ์˜ ๊ฒฝ์šฐ 1,000mg์ž…๋‹ˆ๋‹ค.

3. ํ”Œ๋ผ๋ณด๋…ธ์ด๋“œ๊ฐ€ ํ’๋ถ€ํ•œ ์ถ”์ถœ๋ฌผ 

ํฌ๋„์”จ์†Œ๋‚˜๋ฌด ๊ป์งˆ๋ธ”๋ฃจ๋ฒ ๋ฆฌ์นด์นด์˜ค๋ ˆ์Šค๋ฒ ๋ผํŠธ๋กค(Resveratrol) ๋“ฑ์€ ์šฐ์ˆ˜ํ•œ ํ”Œ๋ผ๋ณด๋…ธ์ด๋“œ(Flavonoid) ๊ณต๊ธ‰์›์ž…๋‹ˆ๋‹ค. ์—ฌ๋Ÿฌ ์ž„์ƒ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ๋‹ค์–‘ํ•œ ํ”Œ๋ผ๋ณด๋…ธ์ด๋“œ ๊ณต๊ธ‰์›์€ ์–ด๋ฆฐ์ด์™€ ์„ฑ์ธ์˜ ์ง‘์ค‘๋ ฅ, ์ฃผ์˜๋ ฅ, ์ธ์ง€ ๋Šฅ๋ ฅ์„ ์ฆ‰๊ฐ์ ์œผ๋กœ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๋“ฑ ๋‡Œ ๊ธฐ๋Šฅ์„ ๊ฐœ์„ ํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋Œ€๋ถ€๋ถ„์˜ ๊ฒฝ์šฐ ํšจ๊ณผ๊ฐ€ ์ฆ‰์‹œ ๋‚˜ํƒ€๋‚˜๊ณ  ์ง€์†์ ์œผ๋กœ ์„ญ์ทจํ•˜๋ฉด ์‹œ๊ฐ„์ด ์ง€๋‚ ์ˆ˜๋ก ํšจ๊ณผ๊ฐ€ ๋”์šฑ ์ข‹์•„์ง‘๋‹ˆ๋‹ค. ์ผ๋ฐ˜์ ์œผ๋กœ ํฌ๋„์”จ ์ถ”์ถœ๋ฌผ์„ ๋งค์ผ 100-200mg์”ฉ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ์ด ๊ถŒ์žฅ๋ฉ๋‹ˆ๋‹ค. 50์„ธ ์ด์ƒ์˜ ์„ฑ์ธ์€ ํ•˜๋ฃจ 1,000mg์˜ ๋ ˆ์Šค๋ฒ ๋ผํŠธ๋กค์„ ์„ญ์ทจํ•˜๋ฉด ๋‡Œ ๊ธฐ๋Šฅ์„ ์ตœ์ ์˜ ์ƒํƒœ๋กœ ์œ ์ง€ํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

์ •์ƒ์ ์ธ ๋‡Œ ๊ธฐ๋Šฅ์„ ์œ ์ง€ํ•˜๋ ค๋ฉด ์ˆ˜๋ฉด์˜ ์งˆ์„ ๋†’์—ฌ์•ผ ํ•ฉ๋‹ˆ๋‹ค

์–‘์งˆ์˜ ์ˆ˜๋ฉด์€ ์ง‘์ค‘๋ ฅ์„ ๋†’์ด๋Š” ๋ฐ ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. ์–‘์งˆ์˜ ์ˆ˜๋ฉด์„ ์ถฉ๋ถ„ํžˆ ์ทจํ•˜์ง€ ์•Š์œผ๋ฉด ๋…์†Œ ์ œ๊ฑฐ ๊ธฐ๋Šฅ๊ณผ ์ „๋ฐ˜์ ์ธ ๋‡Œ ํ™œ๋ ฅ์ด ์ €ํ•˜๋ฉ๋‹ˆ๋‹ค. ๋‡Œ์— ๋…์†Œ๊ฐ€ ์ถ•์ ๋˜๊ณ  ์—๋„ˆ์ง€ ์ƒ์„ฑ์ด ๊ฐ์†Œํ•˜๋ฉด ๊ทธ๋งŒํผ ๋‡Œ ๊ธฐ๋Šฅ๋„ ๋–จ์–ด์ง€๊ฒŒ ๋ฉ๋‹ˆ๋‹ค. 

ํ•˜๋ฃจ๋ฅผ ๋ณด๋‚ด๋Š” ๋ฐ ํ•„์š”ํ•œ ์—๋„ˆ์ง€๊ฐ€ ์ถฉ๋ถ„ํ•˜์ง€ ์•Š์•„ ์ผ๊ณผ๊ฐ€ ๊ธธ์–ด์ง€๋ฉด ๋ธŒ๋ ˆ์ธ ํฌ๊ทธ๋ฅผ ๊ฒช๋Š” ์‚ฌ๋žŒ์ด ๋งŽ์Šต๋‹ˆ๋‹ค. ๋”ฐ๋ผ์„œ ์ถฉ๋ถ„ํ•œ ์–‘์งˆ์˜ ์ˆ˜๋ฉด์„ ์ทจํ•˜๊ธฐ ์œ„ํ•ด ๋…ธ๋ ฅํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. 

์ˆ˜๋ฉด-๊ฐ์„ฑ ์ฃผ๊ธฐ๊ฐ€ ๊ต๋ž€๋˜๋ฉด ์ˆ˜๋ฉด์˜ ์งˆ์ด ๋–จ์–ด์ง€๊ณ  ์ง‘์ค‘๋ ฅ, ์ฃผ์˜๋ ฅ์ด ์ €ํ•˜๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ์ˆ˜๋ฉด ์žฅ์• ๊ฐ€ ์ƒ๊ธฐ๋ฉด ๊ณผ๋„ํ•œ ์ฃผ๊ฐ„ ์กธ๋ฆผ, ์•ผ๊ฐ„ ์ž  ๋ชป ์ด๋ฃธ, ์žฆ์€ ์•ผ๊ฐ„ ๊ฐ์„ฑ๊ณผ ๊ฐ™์€ ์ฆ์ƒ์„ ๊ฒช๊ฒŒ ๋ฉ๋‹ˆ๋‹ค. ๋”ฐ๋ผ์„œ ์ด๋Ÿฐ ๋ฌธ์ œ๊ฐ€ ์žˆ๋Š” ์‚ฌ๋žŒ์€ ํ•ญ์ƒ ์ œํŠธ ๋ ˆ๊ทธ๋ฅผ ๊ฒช๋Š” ๊ฒƒ ๊ฐ™์€ ๊ฒฝํ—˜์„ ํ•˜๊ฒŒ ๋ฉ๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ๋ฌธ์ œ๋Š” ์ˆ˜๋ฉด์˜ ์งˆ์ด ๋‚ฎ์€ ์‚ฌ๋žŒ์ด๋‚˜ ๊ต๋Œ€ ๊ทผ๋ฌด์ž๋‚˜ ๊ณ ๋ น์ž์—๊ฒŒ ํ”ํžˆ ๋‚˜ํƒ€๋‚ฉ๋‹ˆ๋‹ค. 

๋ฉœ๋ผํ† ๋‹Œ, ๋ฉ”ํ‹ธ์ฝ”๋ฐœ๋ผ๋ฏผ, ์ˆ˜๋ฉด-๊ฐ์„ฑ ์ฃผ๊ธฐ ๊ต๋ž€

์ˆ˜๋ฉด-๊ฐ์„ฑ ์ฃผ๊ธฐ๊ฐ€ ๊ต๋ž€๋œ ์‚ฌ๋žŒ์€ ์ทจ์นจ 45๋ถ„ ์ „์— ๋ฉœ๋ผํ† ๋‹Œ(Melatonin)์„, ๊ธฐ์ƒ ํ›„์—๋Š” ๋น„ํƒ€๋ฏผB12์˜ ํ™œ์„ฑ ํ˜•ํƒœ์ธ ๋ฉ”ํ‹ธ์ฝ”๋ฐœ๋ผ๋ฏผ(Methylcobalamin)์„ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. ๋ฉ”ํ‹ธ์ฝ”๋ฐœ๋ผ๋ฏผ์€ ์ˆ˜๋ฉด-๊ฐ์„ฑ ์žฅ์• ๋ฅผ ๊ฒช๋Š” ์‚ฌ๋žŒ์˜ ์ˆ˜๋ฉด์˜ ์งˆ, ์ฃผ๊ฐ„ ์ฃผ์˜๋ ฅ, ์ง‘์ค‘๋ ฅ์„ ํ–ฅ์ƒ์‹œํ‚ฌ ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ๋ฉ”ํ‹ธ์ฝ”๋ฐœ๋ผ๋ฏผ์€ ๊ธฐ๋ถ„๋„ ๊ฐœ์„ ํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

์ž ์ž๊ธฐ ์ „์— ๋งˆ๊ทธ๋„ค์Š˜์„ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ๋„ ์ข‹์Šต๋‹ˆ๋‹ค. ๋ฐค์— ๋งˆ๊ทธ๋„ค์Š˜์„ ์„ญ์ทจํ•˜๋ฉด ๋งˆ์Œ์„ ๊ฐ€๋ผ์•‰ํžˆ๊ณ  ์ŠคํŠธ๋ ˆ์Šค๋ฅผ ์™„ํ™”ํ•˜๋ฉฐ ํŽธ์•ˆํ•œ ์ˆ˜๋ฉด์„ ์ทจํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ๋‹ค์–‘ํ•œ ์ข…๋ฅ˜์˜ ๋งˆ๊ทธ๋„ค์Š˜ ์ค‘์—์„œ ๊ตฌ์—ฐ์‚ฐ ๋งˆ๊ทธ๋„ค์Š˜, ๋ง์‚ฐ์—ผ, ๋น„์Šค๊ธ€๋ฆฌ์‹œ๋„ค์ดํŠธ(Bis-glycinate) ๊ฐ™์€ ํ˜•ํƒœ์˜ ๋งˆ๊ทธ๋„ค์Š˜์„ ์„ ํƒํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. 

์ˆ™๋ฉด์„ ์ทจํ•˜๋Š” ๋ฐ ์–ด๋ ค์›€์„ ๊ฒช๋Š” ์‚ฌ๋žŒ์€ ์ œ๊ฐ€ ์ž‘์„ฑํ•œ ๊ฒŒ์‹œ๊ธ€ ์ตœ๊ณ ์˜ ์ฒœ์—ฐ ์ˆ˜๋ฉด ๋ณด์กฐ์ œ 6๊ฐœ๋ฅผ ์ฝ์–ด๋ณด๋ฉด ๋„์›€์ด ๋˜๋Š” ์ •๋ณด๋ฅผ ์–ป์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์ง‘์ค‘๋ ฅ, ์ฃผ์˜๋ ฅ์„ ๋†’์ด๋Š” ์ตœ๊ณ ์˜ ๋ณด์ถฉ์ œ

์ง€๊ธˆ๊นŒ์ง€ ์†Œ๊ฐœํ•œ ๋ณด์ถฉ์ œ๋Š” ์ง‘์ค‘๋ ฅ ์œ ์ง€์™€ ๊ฐ™์€ ๋‡Œ ๊ธฐ๋Šฅ์— ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ์ด ์™ธ์—๋„ ๋‹ค๋ฅธ ์˜์–‘์†Œ๊ฐ€ ๋” ํ•„์š”ํ•˜๋ฉฐ ํŠนํžˆ ๋‚˜์ด๊ฐ€ ๋“ค์ˆ˜๋ก ์˜์–‘ ์š”๊ตฌ๋Ÿ‰์ด ๋Š˜์–ด๋‚˜๋Š” ์ ๋„ ๋ฌด์‹œํ•  ์ˆ˜ ์—†์Šต๋‹ˆ๋‹ค. ์ง‘์ค‘๋ ฅ๊ณผ ์ฃผ์˜๋ ฅ์„ ํ–ฅ์ƒํ•˜๋Š” ๋ฐ ์ค‘์š”ํ•œ ์˜์–‘์†Œ๋ฅผ ์•Œ์•„๋ด…๋‹ˆ๋‹ค.

1. ์ฒ ๋ถ„๊ณผ ๋‡Œ ๊ธฐ๋Šฅ

์ฒ ๋ถ„ ์ˆ˜์น˜์™€ ์ง‘์ค‘๋ ฅ, ์ฃผ์˜๋ ฅ์„ ์œ ์ง€ํ•˜๋Š” ๋Šฅ๋ ฅ ์‚ฌ์ด์—๋Š” ๋ฐ€์ ‘ํ•œ ์ƒ๊ด€๊ด€๊ณ„๊ฐ€ ์žˆ์Šต๋‹ˆ๋‹ค. ์ฒ ๋ถ„์€ ์–ด๋ฆฐ์ด, ๋น„๊ฑด, ์›”๊ฒฝ ์ค‘์ธ ์—ฌ์„ฑ, ๋…ธ์ธ์—๊ฒŒ ๊ฐ€์žฅ ๊ฒฐํ•๋˜๊ธฐ ์‰ฌ์šด ์˜์–‘์†Œ์ž…๋‹ˆ๋‹ค. ์ฒ ๋ถ„ ๊ฒฐํ•์€ ๋‡Œ ๊ธฐ๋Šฅ์ด ์ €ํ•˜๋˜๋Š” ์ค‘์š”ํ•œ ์›์ธ์ผ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

์ฒ ๋ถ„ ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์•„์ง€๋ฉด ์ฃผ์˜๋ ฅ, ์ฃผ์˜ ์ง€์† ์‹œ๊ฐ„, ๋ˆ๊ธฐ, ๋ณต์žกํ•œ ์ •์‹  ๊ธฐ๋Šฅ ์ˆ˜ํ–‰ ๋Šฅ๋ ฅ์ด ์ €ํ•˜๋ฉ๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ์ฒ ๋ถ„์„ ๋ณด์ถฉํ•˜๋ฉด ์ธ์ง€ ๊ธฐ๋Šฅ์„ ๊ฐœ์„ ํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. ์ฒ ๋ถ„์€ ์ ํ˜ˆ๊ตฌ์— ์‚ฐ์†Œ๋ฅผ ์šด๋ฐ˜ํ•˜๋Š” ์—ญํ• ์„ ํ•  ๋ฟ ์•„๋‹ˆ๋ผ ํšจ์†Œ๊ฐ€ ๋‡Œ์™€ ์‹ ์ฒด์˜ ์—๋„ˆ์ง€ ์ƒ์„ฑ์— ๊ด€์—ฌํ•  ๋•Œ ์—ฌ๋Ÿฌ ๊ธฐ๋Šฅ์„ ์ˆ˜ํ–‰ํ•˜๋Š” ์ค‘์š”ํ•œ ์˜์–‘์†Œ์ž…๋‹ˆ๋‹ค.

์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ์–ด๋ฆฐ์ด์™€ ์„ฑ์ธ์€ ์ฒ ๋ถ„์ด ์•ฝ๊ฐ„๋งŒ ๊ฒฐํ•๋˜์–ด๋„ ๋‡Œ ๊ธฐ๋Šฅ์ด ์†์ƒ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ์ฒด๋‚ด ์ฒ ๋ถ„ ์ €์žฅ๋Ÿ‰์„ ์ถฉ๋ถ„ํ•œ ์ˆ˜์ค€์œผ๋กœ ๋ณต๊ตฌํ•˜๋ฉด ์ด๋Ÿฌํ•œ ๋ฌธ์ œ๋ฅผ ์™„์ „ํžˆ ํ•ด๊ฒฐํ•  ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. 

18์„ธ ๋ฏธ๋งŒ์ธ ๊ฒฝ์šฐ ์ฒ ๋ถ„์„ ํ•˜๋ฃจ ๊ถŒ์žฅ์„ญ์ทจ๋Ÿ‰๋งŒํผ ๋ณด์ถฉํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. ์ฒ ๋ถ„ ๊ฒฐํ• ์œ„ํ—˜์ด ์žˆ๋Š” 18์„ธ ์ด์ƒ์˜ ์‚ฌ๋žŒ์€ ํ˜ˆ์•ก ๊ฒ€์‚ฌ๋ฅผ ํ†ตํ•ด ํ˜ˆ์ฒญ ํŽ˜๋ฆฌํ‹ด(Ferritin) ๋†๋„๋ฅผ ์ธก์ •ํ•ด ์ฒ ๋ถ„ ์ƒํƒœ๋ฅผ ํ‰๊ฐ€ํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

๊ถŒ์žฅํ•˜๋Š” ์ฒ ๋ถ„ ํ˜•ํƒœ๋Š” ํ”ผ๋กœ์ธ์‚ฐ์ œ์ด์ฒ (Ferric pyrophosphate)๊ณผ ์ฒ ๋ถ„ ๋น„์Šค๊ธ€๋ฆฌ์‹œ๋„ค์ดํŠธ(Ferrous bisglycinate)์ž…๋‹ˆ๋‹ค. ๋‹ค๋ฅธ ํ˜•ํƒœ์˜ ์ฒ ๋ถ„๊ณผ๋Š” ๋‹ฌ๋ฆฌ ์ด๋Ÿฌํ•œ ์ฒ ๋ถ„์€ ์œ„์žฅ๊ด€ ๋ถ€์ž‘์šฉ์„ ์œ ๋ฐœํ•˜์ง€ ์•Š๊ธฐ ๋•Œ๋ฌธ์ž…๋‹ˆ๋‹ค. 

2. ์ธ์ง€๋ ฅ ๋ฐ ๊ธฐ์–ต๋ ฅ์„ ๋†’์ด๊ณ  ์ŠคํŠธ๋ ˆ์Šค๋ฅผ ์™„ํ™”ํ•˜๋Š” ๊ฐ€๋ฐ”

์ตœ๊ทผ ์ž„์ƒ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ์ฒœ์—ฐ ํ˜•ํƒœ์˜ ๊ฐ€๋ฐ”(GABA)์ธ ํŒŒ๋งˆ๊ฐ€๋ฐ”(PharmaGABA)๋Š” ์–ด๋ฆฐ์ด์™€ ์„ฑ์ธ์˜ ์ •์‹  ๊ธฐ๋Šฅ์„ ํ–ฅ์ƒํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ์ˆ˜๋ฉด์˜ ์งˆ์„ ๊ฐœ์„ ํ•˜๋Š” ๋ฐ๋„ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค.

ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์•ŒํŒŒํŒŒ ์ƒ์„ฑ์„ ์ด‰์ง„ํ•˜๋ฉด์„œ ๋ฒ ํƒ€ํŒŒ(์‹ ๊ฒฝ๊ณผ๋ฏผ, ์‚ฐ๋ฐœ์  ์‚ฌ๊ณ , ๊ณผ์ž‰ ํ–‰๋™๊ณผ ๊ด€๋ จ๋จ)๋ฅผ ๊ฐ์†Œ์‹œํ‚ต๋‹ˆ๋‹ค. ์•ŒํŒŒํŒŒ๊ฐ€ ์ฆ๊ฐ€ํ•˜๋ฉด ์ง‘์ค‘์  ์‚ฌ๊ณ ๊ฐ€ ์ด‰์ง„๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ๋ฐค์— ์ •์‹ ์ด ๊ณ„์† ๊นจ์–ด ์žˆ์–ด ์ž ๋“œ๋Š” ๋ฐ ์–ด๋ ค์›€์„ ๊ฒช๋Š” ์‚ฌ๋žŒ๋“ค์—๊ฒŒ๋„ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. 

ํŒŒ๋งˆ๊ฐ€๋ฐ”์™€ ๊ด€๋ จํ•ด ์—ฌ๋Ÿฌ ๊ฑด์˜ ํฅ๋ฏธ๋กœ์šด ์ž„์ƒ ์—ฐ๊ตฌ๊ฐ€ ์ˆ˜ํ–‰๋œ ๋ฐ” ์žˆ์Šต๋‹ˆ๋‹ค. ์ผ๋ณธ ๊ต๋ฆฐ ๋Œ€ํ•™๊ต ์˜๊ณผ๋Œ€ํ•™์˜ ํ•œ ์—ฐ๊ตฌ์—์„œ๋Š” 6ํ•™๋…„ ํ•™์ƒ๋“ค์„ ๋‘ ๊ทธ๋ฃน์œผ๋กœ ๋‚˜๋ˆ„์–ด ๊ฐ๊ฐ 100mg์˜ ํŒŒ๋งˆ๊ฐ€๋ฐ”์™€ ์œ„์•ฝ์„ ํˆฌ์—ฌํ–ˆ์Šต๋‹ˆ๋‹ค. ๊ทธ๋‹ค์Œ ํ•™์ƒ๋“ค์€ ์ˆ˜ํ•™ ์‹œํ—˜์„ ์น˜๋ €๊ณ  ์ŠคํŠธ๋ ˆ์Šค์˜ ์ง•ํ›„ ๋ฐ ๋Š๋‚Œ์— ๋Œ€ํ•ด ํ‰๊ฐ€๋ฐ›์•˜์Šต๋‹ˆ๋‹ค. ๊ทธ ๊ฒฐ๊ณผ๋Š” ๋†€๋ผ์› ์Šต๋‹ˆ๋‹ค. ํŒŒ๋งˆ๊ฐ€๋ฐ” ์„ญ์ทจ ๊ทธ๋ฃน์˜ ํ‰๊ท  ๋‹ต๋ณ€ ์ˆ˜๋Š” ์œ„์•ฝ ๊ทธ๋ฃน๋ณด๋‹ค 20% ๋” ๋†’์•˜๊ณ  ์ •๋‹ต ์ˆ˜ ์—ญ์‹œ 20% ์ฆ๊ฐ€ํ–ˆ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ๊ฒฐ๊ณผ๋Š” ํŒŒ๋งˆ๊ฐ€๋ฐ”๊ฐ€ ์•„๋™๋“ค์ด ์ƒ๊ฐํ•˜๋Š” ์†๋„๋ฅผ ๋น ๋ฅด๊ฒŒ ํ–ˆ๊ณ  ์ •๋‹ต๋ฅ ์„ ๋†’์ด๋Š” ๋ฐ ๋„์›€์ด ๋˜์—ˆ์Œ์„ ์‹œ์‚ฌํ•ฉ๋‹ˆ๋‹ค.

๋˜ํ•œ ์ด ์—ฐ๊ตฌ์—์„œ๋Š” ํƒ€์•ก์— ํฌํ•จ๋œ ์ŠคํŠธ๋ ˆ์Šค ๊ด€๋ จ ํ˜ธ๋ฅด๋ชฌ์˜ ์–‘๊ณผ ์—ฐ๊ตฌ ์ค‘์— ๊ฒฝํ—˜ํ•œ ๋ถˆ์•ˆ ์ •๋„์™€ ๊ฐ™์€ ์ŠคํŠธ๋ ˆ์Šค์˜ ์ค‘์š”ํ•œ ์ง€ํ‘œ๋ฅผ ์กฐ์‚ฌํ–ˆ์Šต๋‹ˆ๋‹ค. ์ŠคํŠธ๋ ˆ์Šค์— ๋Œ€ํ•œ ์ฃผ๊ด€์  ์ธก์ •์น˜์™€ ๊ฐ๊ด€์  ์ธก์ •์น˜๋ฅผ ๋ถ„์„ํ•œ ๊ฒฐ๊ณผ ํŒŒ๋งˆ๊ฐ€๋ฐ” ์„ญ์ทจ ๊ทธ๋ฃน์ด ์œ„์•ฝ ๊ทธ๋ฃน๋ณด๋‹ค ํ›จ์”ฌ ๋” ํŽธ์•ˆํ•œ ๋งˆ์Œ์œผ๋กœ ๋” ๋†’์€ ์ง‘์ค‘๋ ฅ์„ ๋ฐœํœ˜ํ•œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

์—ฌ๋Ÿฌ ์ž„์ƒ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์„ฑ์ธ์—๊ฒŒ๋„ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. 40์„ธ ์ด์ƒ์˜ ์„ฑ์ธ์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ ์—ฐ๊ตฌ์—์„œ ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์ง‘์ค‘๋ ฅ์„ ์ œ์–ดํ•˜๊ณ  ์œ ์ง€ํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์‹œ๊ฐ์  ๋˜๋Š” ์ถ”์ƒ์  ์ •๋ณด๋ฅผ ์ถ”๋ก ํ•˜๊ณ  ์ดํ•ดํ•˜๋Š” ๋Šฅ๋ ฅ์„ ํ–ฅ์ƒํ–ˆ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋กœ ์ธํ•ด ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ๋…ผ๋ฆฌ์  ์‚ฌ๊ณ ๋ฅผ ํ–ฅ์ƒํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์ง„ ์ตœ์ดˆ์˜ ๋ฌผ์งˆ์ด ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ์ด ์™ธ์—๋„ ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ๋‹จ๊ธฐ ๋ฐ ์žฅ๊ธฐ ๊ธฐ์–ต๋ ฅ์„ ๊ฐœ์„ ํ–ˆ์Šต๋‹ˆ๋‹ค. 

ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์ŠคํŠธ๋ ˆ์Šค๋‚˜ ๋ถˆ์•ˆ๊ฐ์œผ๋กœ ์ธํ•ด ์ €ํ•˜๋œ ์ง‘์ค‘๋ ฅ์„ ๊ฐœ์„ ํ•˜๋Š” ๋ฐ ์ข‹์Šต๋‹ˆ๋‹ค. ๋น„ํŒ์  ์‚ฌ๊ณ ์™€ ๊ฐ™์€ ๊ณ ๊ธ‰ ๋‡Œ ๊ธฐ๋Šฅ์€ ํŽธ์•ˆํ•œ ์ƒํƒœ์—์„œ ๋” ํ–ฅ์ƒ๋ฉ๋‹ˆ๋‹ค. ์ฝ”๋ฅดํ‹ฐ์†”(Cortisol) ๊ฐ™์€ ์ŠคํŠธ๋ ˆ์Šค ํ˜ธ๋ฅด๋ชฌ์€ ์ด๋Ÿฌํ•œ ๊ณ ๊ธ‰ ๋‡Œ ๊ธฐ๋Šฅ์„ ๋ฐฉํ•ดํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ํŒŒ๋งˆ๊ฐ€๋ฐ”๋Š” ์ฝ”๋ฅดํ‹ฐ์†”์„ ๊ฐ์†Œ์‹œํ‚ค๊ณ  ๊ธด์žฅ๊ฐ์„ ์™„ํ™”์‹œํ‚ค๋ฉฐ ๋‡Œ ์—๋„ˆ์ง€์™€ ์ง‘์ค‘๋ ฅ์„ ํ–ฅ์ƒํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

3. ์ง‘์ค‘๋ ฅ์„ ํ–ฅ์ƒํ•˜๋Š” ์นดํŽ˜์ธ๊ณผ L-ํ…Œ์•„๋‹Œ

์นดํŽ˜์ธ์€ ๋‡Œ ํ™œ๋™์„ ์ด‰์ง„ํ•˜๊ณ  ์ฃผ์˜๋ ฅ๊ณผ ์ง‘์ค‘๋ ฅ์„ ๋†’์ด๋Š” ๋ฐ ํšจ๊ณผ์ ์ž…๋‹ˆ๋‹ค. ๊ทธ๋ž˜์„œ ์นดํŽ˜์ธ์„ ์„ญ์ทจํ•˜๋ฉด ๋ฐ˜๋ณต ์ž‘์—… ์‹œ ์ˆ˜ํ–‰ ์†๋„๋ฅผ ๋†’์ด๊ณ  ์‹ค์ˆ˜๋ฅผ ์ค„์ผ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

์ปคํ”ผ๋Š” ๊ฐ€์žฅ ์ธ๊ธฐ ์žˆ๋Š” ์นดํŽ˜์ธ ๊ณต๊ธ‰์›์ž…๋‹ˆ๋‹ค. ๋…น์ฐจ์™€ ํ™์ฐจ๊ณผ๋ผ๋‚˜(Guarana)์—๋„ ์นดํŽ˜์ธ์ด ํ•จ์œ ๋˜์–ด ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ์กธ์Œ์„ ์ซ“๋Š” ์ผ๋ฐ˜ ์˜์•ฝํ’ˆ์ด๋‚˜ ๋ณด์ถฉ์ œ๋ฅผ ํ†ตํ•ด์„œ๋„ ์นดํŽ˜์ธ์„ ์„ญ์ทจํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

์นดํŽ˜์ธ์€ ์•„๋ฐ๋…ธ์‹ (Adenosine)์ด ๋‡Œ์„ธํฌ ์ˆ˜์šฉ์ฒด์— ๊ฒฐํ•ฉํ•˜๋Š” ๊ฒƒ์„ ์ฐจ๋‹จํ•˜๋Š” ์ž‘์šฉ์„ ํ•ฉ๋‹ˆ๋‹ค. ์•„๋ฐ๋…ธ์‹ ์€ ๋‡Œ์„ธํฌ ์ˆ˜์šฉ์ฒด์— ๊ฒฐํ•ฉํ•˜๋ฉด ์กธ์Œ์„ ์œ ๋„ํ•ฉ๋‹ˆ๋‹ค. ์•„๋ฐ๋…ธ์‹ ์€ ๋‚ฎ ๋™์•ˆ ๊ณ„์† ์ฒด๋‚ด์— ๋ˆ„์ ๋˜๋‹ค๊ฐ€ ๊ฒฐ๊ตญ์—๋Š” ์กธ์Œ์„ ์ผ์œผํ‚ต๋‹ˆ๋‹ค. ์นดํŽ˜์ธ์˜ ๋ถ„์ž ๊ตฌ์กฐ๋Š” ์•„๋ฐ๋…ธ์‹ ๊ณผ ์œ ์‚ฌํ•ฉ๋‹ˆ๋‹ค. ๋”ฐ๋ผ์„œ ์นดํŽ˜์ธ์€ ์•„๋ฐ๋…ธ์‹ ์˜ ์ž‘์šฉ์„ ์ฐจ๋‹จํ•ด ์ฃผ์˜๋ ฅ์„ ๋†’์ด๋ฉฐ, ๊ณ ์šฉ๋Ÿ‰์œผ๋กœ ์‚ฌ์šฉํ•  ๊ฒฝ์šฐ ๊ธฐ๋ฏผ์„ฑ์„ ๊ทน๋„๋กœ ํ–ฅ์ƒํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ์นดํŽ˜์ธ์€ ๋„ํŒŒ๋ฏผ(Dopamine), ์„ธ๋กœํ† ๋‹Œ(Serotonin)๊ณผ ๊ฐ™์€ ์‹ ๊ฒฝ์ „๋‹ฌ๋ฌผ์งˆ์˜ ๋ฐฉ์ถœ์„ ์ด‰์ง„ํ•ฉ๋‹ˆ๋‹ค. ๋Œ€๋ถ€๋ถ„์˜ ์‚ฌ๋žŒ์€ ํ•˜๋ฃจ 1-2์ž”์˜ ์ปคํ”ผ ๋˜๋Š” 150-200mg์˜ ์นดํŽ˜์ธ์„ ์„ญ์ทจํ•ด๋„ ๋ถ€์ž‘์šฉ์ด ์ƒ๊ธฐ์ง€ ์•Š์Šต๋‹ˆ๋‹ค.

์นดํŽ˜์ธ์˜ ๊ฐ์„ฑ ํšจ๊ณผ์— ๋ฏผ๊ฐํ•œ ์‚ฌ๋žŒ์€ 40-75mg์˜ ์นดํŽ˜์ธ๊ณผ 100mg์˜ L-ํ…Œ์•„๋‹Œ(L-theanine)์„ ํ•จ๊ป˜ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. 8-15์„ธ์˜ ์†Œ๋…„์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ ์—ฐ๊ตฌ๋ฅผ ๋น„๋กฏํ•œ ์—ฌ๋Ÿฌ ์—ฐ๊ตฌ์—์„œ๋Š” ์นดํŽ˜์ธ๊ณผ L-ํ…Œ์•„๋‹Œ์„ ์ด์ฒ˜๋Ÿผ ์กฐํ•ฉํ•ด ์„ญ์ทจํ•˜๋ฉด ๊ธฐ๋ฏผ์„ฑ, ์ฃผ์˜๋ ฅ, ์ธ์ง€๋ ฅ์ด ๊ฐœ์„ ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ์—ฐ๊ตฌ๋“ค์€ ์นดํŽ˜์ธ๊ณผ L-ํ…Œ์•„๋‹Œ์„ ์กฐํ•ฉํ•œ ๊ฒฝ์šฐ์™€ ๋‘ ์„ฑ๋ถ„์„ ๋‹จ๋…์œผ๋กœ ์‚ฌ์šฉํ•œ ๊ฒฝ์šฐ์˜ ํšจ๊ณผ๋ฅผ ๋น„๊ตํ–ˆ์Šต๋‹ˆ๋‹ค. ๊ทธ ๊ฒฐ๊ณผ ๋‘ ์„ฑ๋ถ„์˜ ํ˜ผํ•ฉ๋ฌผ์ด ๊ฐ€์žฅ ํฐ ๊ฐœ์„  ํšจ๊ณผ๋ฅผ ๋ณด์ธ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. 

๋…น์ฐจ๋ฅ˜ ์ค‘์—์„œ๋„ ํŠนํžˆ ๋ง์ฐจ๋Š” ์นดํŽ˜์ธ๊ณผ L-ํ…Œ์•„๋‹Œ์„ ํ•จ์œ ํ•˜๊ณ  ์žˆ์œผ๋ฉฐ ์Œ๋ฃŒ ํ˜•ํƒœ๋กœ ์„ญ์ทจํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์•„๋™์ด๋‚˜ ์„ฑ์ธ์ด ๋งค์ผ ๋ง์ฐจ๋ฅผ ๋งˆ์‹œ๊ฑฐ๋‚˜ ๋‹ค๋ฅธ ๋ฐฉ๋ฒ•์œผ๋กœ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ์„ ์ข‹์•„ํ•˜์ง€ ์•Š๋Š”๋‹ค๋ฉด ๋ณด์ถฉ์ œ ํ˜•ํƒœ์˜ L-ํ…Œ์•„๋‹Œ์„ ์‚ฌ์šฉํ•˜๋Š” ๊ฒƒ๋„ ์ข‹์€ ๋ฐฉ๋ฒ•์ž…๋‹ˆ๋‹ค. ์„ฑ์ธ์ด ๋งค์ผ 200mg์˜ L-ํ…Œ์•„๋‹Œ๋งŒ์„ ์„ญ์ทจํ•ด๋„ ์ธ์ง€ ๊ธฐ๋Šฅ์„ ํ–ฅ์ƒํ•˜๋Š” ๋ฐ ์ƒ๋‹นํžˆ ํšจ๊ณผ์ ์ธ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

L-ํ…Œ์•„๋‹Œ์€ ํŒŒ๋งˆ๊ฐ€๋ฐ”์ฒ˜๋Ÿผ ์•ŒํŒŒํŒŒ ์ƒ์„ฑ์„ ์ด‰์ง„ํ•˜๊ณ  ๋ฒ ํƒ€ํŒŒ๋Š” ๊ฐ์†Œ์‹œํ‚ต๋‹ˆ๋‹ค. ํŒŒ๋งˆ๊ฐ€๋ฐ”์™€ L-ํ…Œ์•„๋‹Œ์€ ๋ถˆ์•ˆ ์œ ๋ฐœ๊ณผ ๊ฐ™์€ ์นดํŽ˜์ธ์˜ ๋ถ€์ •์ ์ธ ํšจ๊ณผ๋ฅผ ์–ต์ œํ•˜๋Š” ๋™์‹œ์— ์ง‘์ค‘๋ ฅ ๋ฐ ์ฃผ์˜๋ ฅ ํ–ฅ์ƒ๊ณผ ๊ฐ™์€ ์นดํŽ˜์ธ์˜ ๊ธ์ •์  ํšจ๊ณผ๋Š” ๊ฐ•ํ™”ํ•ฉ๋‹ˆ๋‹ค. ๋˜ํ•œ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด 8-12์„ธ์˜ ์†Œ๋…„์ด ๋งค์ผ 2ํšŒ 200mg์˜ L-ํ…Œ์•„๋‹Œ์„ ์„ญ์ทจํ•˜๋ฉด ์ˆ˜๋ฉด์˜ ์งˆ์ด ํ–ฅ์ƒ๋ฉ๋‹ˆ๋‹ค. 

4. ์ •์‹  ๊ธฐ๋Šฅ์„ ๊ฐœ์„ ํ•˜๋Š” ์•„์Šˆ์™€๊ฐ„๋‹ค

ํ•™๋ช…์ด ์œ„ํƒ€๋‹ˆ์•„ ์†œ๋‹ˆํŽ˜๋ผ(Withania somnifera)์ธ ์•„์Šˆ์™€๊ฐ„๋‹ค(Ashwagandha)๋Š” ์ •์‹  ๋ฐ ์‹ ์ฒด ๊ธฐ๋Šฅ, ์ˆ˜๋ฉด์˜ ์งˆ์„ ๊ฐœ์„ ํ•˜๋ฉฐ ์ŠคํŠธ๋ ˆ์Šค๋ฅผ ์™„ํ™”ํ•˜๊ณ  ์—๋„ˆ์ง€ ์ˆ˜์ค€์„ ๋†’์ด๋Š” ๋“ฑ ๋‹ค์–‘ํ•œ ํšจ๋Šฅ์„ ๋‚˜ํƒ€๋‚ด๋Š” ํ—ˆ๋ธŒ ์„ธ๊ณ„์˜ ์Šˆํผ์Šคํƒ€์ž…๋‹ˆ๋‹ค.

๋ฌด์—‡๋ณด๋‹ค๋„ ์•„์Šˆ์™€๊ฐ„๋‹ค๋Š” ์ŠคํŠธ๋ ˆ์Šค ๋Œ€์ฒ˜ ๋Šฅ๋ ฅ์„ ๋•๋Š” ๊ฐ•์žฅ์ œ๋กœ ์ž˜ ์•Œ๋ ค์ ธ ์žˆ์Šต๋‹ˆ๋‹ค. ์ŠคํŠธ๋ ˆ์Šค๋Š” ์ƒ๊ฐ, ์ง‘์ค‘, ์ฃผ์˜๋ ฅ ์œ ์ง€๋ฅผ ๋ฐฉํ•ดํ•˜๋Š” ์ค‘์š”ํ•œ ์š”์ธ์ž…๋‹ˆ๋‹ค. ์—ฌ๋Ÿฌ ์ž„์ƒ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ์•„์Šˆ์™€๊ฐ„๋‹ค๋Š” ์ง‘์ค‘๋ ฅ, ์‚ฌ๊ณ ๋ ฅ(์ธ์ง€ ๊ธฐ๋Šฅ) ๋“ฑ ๋‹ค์–‘ํ•œ ๋‡Œ ๊ธฐ๋Šฅ์— ๋Œ€ํ•œ ์ธก์ •์น˜๋ฅผ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

์•„์Šˆ์™€๊ฐ„๋‹ค๊ฐ€ ์ด๋Ÿฌํ•œ ํšจ๋Šฅ์„ ๋‚˜ํƒ€๋‚ด๋Š” ๋‹ค์–‘ํ•œ ์ด์œ  ์ค‘ ํ•˜๋‚˜๋Š” ์•„์Šˆ์™€๊ฐ„๋‹ค ์„ฑ๋ถ„์ด ๋‡Œ์˜ ํŠน์ • ๋ถ€์œ„๋ฅผ ๋ณดํ˜ธํ•˜๊ณ  ํ–ฅ์ƒ์‹œํ‚ค๊ธฐ ๋•Œ๋ฌธ์ž…๋‹ˆ๋‹ค. ์•„์Šˆ์™€๊ฐ„๋‹ค์˜ ๋˜ ๋‹ค๋ฅธ ์ค‘์š”ํ•œ ํŠน์„ฑ์œผ๋กœ๋Š” ์ˆ˜๋ฉด์˜ ์งˆ์„ ๊ฐœ์„ ํ•˜๊ณ  ์ŠคํŠธ๋ ˆ์Šค์— ๋Œ€์ฒ˜ํ•˜๋Š” ๋Šฅ๋ ฅ์„ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๊ฒƒ์„ ๋“ค ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์•„์Šˆ์™€๊ฐ„๋‹ค๋Š” ์ฒญ์†Œ๋…„๋ถ€ํ„ฐ ๊ณ ๋ น์ž์— ์ด๋ฅด๊ธฐ๊นŒ์ง€ ๊ฑฐ์˜ ๋ชจ๋“  ์—ฐ๋ น์ธต์— ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์ง€๋งŒ, ์ŠคํŠธ๋ ˆ์Šค๋ฅผ ๋งŽ์ด ๋ฐ›๋Š” ์ดˆ๊ธฐ ์„ฑ์ธ๊ธฐ์— ํ•ด๋‹นํ•˜๋Š” ์‚ฌ๋žŒ์—๊ฒŒ ํŠนํžˆ ์œ ์ตํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

5. ๊ธฐ์–ต๋ ฅ๊ณผ ์ธ์ง€๋ ฅ์„ ๋†’์ด๋Š” ์ฝ”ํํ…๊ณผ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ

๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„ ๊ธฐ๋Šฅ์„ ์ฆ์ง„ํ•˜๋Š” ์ฝ”ํํ… ๋ฐ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ(Pyrroloquinoline quinon)์€ ํ•จ๊ป˜ ์ž‘์šฉํ•˜์—ฌ ๊ธฐ์–ต๋ ฅ๊ณผ ์ธ์ง€๋ ฅ์„ ํšจ๊ณผ์ ์œผ๋กœ ๊ฐœ์„ ํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค.  ์ด๋ฏธ ์ž˜ ์•Œ๋ ค์ ธ ์žˆ๋Š” ์ฝ”ํํ…๊ณผ๋Š” ๋‹ฌ๋ฆฌ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ์€ ์ด์ œ ๋Œ€์ค‘ํ™”๋˜๊ธฐ ์‹œ์ž‘ํ•œ ์˜์–‘์†Œ์ž…๋‹ˆ๋‹ค. ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ์€ ํŠนํžˆ ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„๊ฐ€ ์†์ƒ๋˜์ง€ ์•Š๋„๋ก ๋ณดํ˜ธํ•˜๋Š” ๊ฐ•๋ ฅํ•œ ํ•ญ์‚ฐํ™”์ œ์ž…๋‹ˆ๋‹ค. ๋˜ํ•œ ๋…ธํ™” ์„ธํฌ ๋‚ด์—์„œ ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„ ์‹ ์ƒ(Mitochondrial biogenesis), ์ฆ‰ ์ƒˆ๋กœ์šด ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„์˜ ์ž๋ฐœ์ ์ธ ์ƒ์„ฑ์„ ์ด‰์ง„ํ•ฉ๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ํšจ๋Šฅ์€ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ์ด ํ•ญ๋…ธํ™” ์„ฑ๋ถ„์œผ๋กœ ์ฃผ๋ชฉ๋ฐ›๋Š” ์ด์œ ์ž…๋‹ˆ๋‹ค.

ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ์€ ๋‹จ๋…์œผ๋กœ ์‚ฌ์šฉํ•ด๋„ ํšจ๊ณผ์ ์ด์ง€๋งŒ ์ฝ”ํํ…๊ณผ ๋ณ‘์šฉํ•˜๋ฉด ๋” ๋›ฐ์–ด๋‚œ ํšจ๊ณผ๋ฅผ ๋ณด์ด๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. 40-70์„ธ ์‚ฌ์ด์˜ ์ค‘๋…„ ๋ฐ ๋…ธ์ธ 71๋ช…์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ ์—ฐ๊ตฌ์—์„œ ๋งค์ผ 20mg์˜ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ์„ ๋ณด์ถฉํ•œ ์‹คํ—˜๊ตฐ์€ ์œ„์•ฝ๋Œ€์กฐ๊ตฐ์— ๋น„ํ•ด ๊ณ ๊ธ‰ ์ธ์ง€๊ธฐ๋Šฅ ๊ฒ€์‚ฌ ๊ฒฐ๊ณผ๊ฐ€ ํ–ฅ์ƒ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ์ฝ”ํํ… 300mg๊ณผ ํ•จ๊ป˜ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ 20mg์„ ํˆฌ์—ฌ๋ฐ›์€ ๊ทธ๋ฃน์€ ํ›จ์”ฌ ๋” ์šฐ์ˆ˜ํ•œ ๊ฒฐ๊ณผ๋ฅผ ๋‚˜ํƒ€๋ƒˆ์Šต๋‹ˆ๋‹ค. ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ๊ณผ ์ฝ”ํํ…์€ ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„์˜ ์—๋„ˆ์ง€ ์ƒ์‚ฐ์— ๊ด€์—ฌํ•œ๋‹ค๋Š” ์ ์—์„œ ์ด๋Ÿฌํ•œ ๊ฒฐ๊ณผ๋Š” ๋‹น์—ฐํ•˜๋‹ค๊ณ  ๋ณผ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

50์„ธ ์ด์ƒ์˜ ์‚ฌ๋žŒ์ด ์ฝ”ํํ… ๋ฐ ํ”ผ๋กค๋กœํ€ด๋†€๋ฆฐ ํ€ด๋…ผ๊ฐ™์ด ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„ ๊ธฐ๋Šฅ์„ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๋ณด์ถฉ์ œ๋ฅผ ์„ญ์ทจํ•˜๋ฉด ์ง‘์ค‘๋ ฅ, ์ฃผ์˜๋ ฅ๋ฟ ์•„๋‹ˆ๋ผ ๊ธฐ์–ต๋ ฅ, ์ธ์ง€๋ ฅ์„ ํ–ฅ์ƒ์‹œํ‚ค๋Š” ๋ฐ๋„ ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. 

6. ์ง‘์ค‘๋ ฅ์„ ๋•๋Š” ํ›„ํผ์ง„A

ํ›„ํผ์ง„A(Huperzine-A, Hup A)๋Š” ํ•™๋ช…์ด ํ›„ํผ์ง€์•„ ์„ธ๋ผํƒ€(Huperzia Serrata)์ธ ์ค‘๊ตญ ์„์†ก์— ์ž์—ฐ์ ์œผ๋กœ ํ•จ์œ ๋œ ๋ฌผ์งˆ์ž…๋‹ˆ๋‹ค. ๋‹ค์–‘ํ•œ ์ด์ค‘๋งน๊ฒ€ ์ž„์ƒ์‹œํ—˜์„ ํ†ตํ•ด ๊ด‘๋ฒ”์œ„ํ•˜๊ฒŒ ์—ฐ๊ตฌ๋˜๊ณ  ์žˆ๋Š” ํ›„ํผ์ง„A๋Š” ์ง‘์ค‘๋ ฅ, ์ธ์ง€ ๊ธฐ๋Šฅ์„ ํ–ฅ์ƒ์‹œํ‚ค๊ณ  ์ €ํ•˜๋œ ๊ธฐ์–ต๋ ฅ์„ ๊ฐœ์„ ํ•˜๋Š” ๋ฐ ์œ ์˜๋ฏธํ•œ ํšจ๊ณผ๋ฅผ ๋ณด์ด๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ํ›„ํผ์ง„A๋Š” ๊ธฐ์–ต๋ ฅ๊ณผ ์ง‘์ค‘๋ ฅ์— ์ค‘์š”ํ•œ ๋‡Œ ๋ฌผ์งˆ์ธ ์•„์„ธํ‹ธ์ฝœ๋ฆฐ(Acetylcholine)์˜ ๋ถ„ํ•ด๋ฅผ ์–ต์ œํ•ฉ๋‹ˆ๋‹ค. ํ›„ํผ์ง„A๋Š” ์•„์„ธํ‹ธ์ฝœ๋ฆฐ์˜ ๋ถ„ํ•ด๋ฅผ ๋ฐฉ์ง€ํ•จ์œผ๋กœ์จ ์ง‘์ค‘๋ ฅ, ์‚ฌ๊ณ ๋ ฅ, ๊ธฐ์–ต๋ ฅ์„ ๊ฐœ์„ ํ•ฉ๋‹ˆ๋‹ค. 

๋˜ํ•œ ๋‹ค์–‘ํ•œ ์‹ ๊ฒฝ๋…์œผ๋กœ ์ธํ•œ ๋‡Œ์„ธํฌ ์†์ƒ์„ ๋ฐฉ์ง€ํ•˜๊ณ  ๋‡Œ์˜ ํ•ญ์‚ฐํ™” ํšจ์†Œ ํ™œ๋™์„ ์ฆ์ง„ํ•˜๋ฉฐ ์ƒˆ๋กœ์šด ๋‡Œ์„ธํฌ ํ˜•์„ฑ์„ ์ด‰์ง„ํ•ฉ๋‹ˆ๋‹ค. ํ›„ํผ์ง„A๋Š” ๋งค์ผ 2ํšŒ 200mcg์„ ์„ญ์ทจํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. ์ •์ œ๋˜์ง€ ์•Š์€ ํ›„ํผ์ง€์•„ ์ œ์ œ ๋Œ€์‹  ์ˆœ์ˆ˜ํ•œ ํ›„ํผ์ง„A๋ฅผ ์‚ฌ์šฉํ•˜๋Š” ๊ฒƒ์ด ์•ˆ์ „ํ•˜๊ณ  ํšจ๊ณผ์ ์ž…๋‹ˆ๋‹ค. 

๊ฒฐ๋ก 

๊ฑด๊ฐ•์„ ์ฆ์ง„ํ•˜๋Š” ์‹๋‹จ๊ณผ ์ƒํ™œ์Šต๊ด€์„ ๋”ฐ๋ฅด๋ฉด ๋‡Œ๊ฐ€ ์ตœ์ ์˜ ์ƒํƒœ๋กœ ๊ธฐ๋Šฅํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ๋ณด์ถฉ์ œ๋Š” ๋‡Œ ๊ฑด๊ฐ•์„ ์ฆ์ง„ํ•ด ์ง‘์ค‘๋ ฅ๊ณผ ์ฃผ์˜๋ ฅ์„ ํฌ๊ฒŒ ํ–ฅ์ƒ์‹œํ‚ฌ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ๋ณด์ถฉ์ œ๋Š” ๊ฑด๊ฐ•ํ•œ ์‹๋‹จ๊ณผ ์–‘์งˆ์˜ ์ˆ˜๋ฉด์„ ์™„์ „ํžˆ ๋Œ€์ฒดํ•˜์ง€ ๋ชปํ•ฉ๋‹ˆ๋‹ค. ์–ด๋–ค ์—ฐ๋ น์˜ ์‚ฌ๋žŒ์ด๋“  ์ด ์‚ฌ์‹ค์„ ์—ผ๋‘์— ๋‘๊ณ  ์žฅ๊ธฐ์ ์ธ ๊ณ„ํš์„ ์„ธ์šฐ๋ฉด ๋‡Œ๋ฅผ ๊ฑด๊ฐ•ํ•˜๊ฒŒ ์œ ์ง€ํ•  ์ˆ˜ ์žˆ์„ ๊ฒƒ์ž…๋‹ˆ๋‹ค.

์ฐธ๊ณ ๋ฌธํ—Œ:

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  2. Hardy AL, Pouteau E, Marquez D, et al. Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients. 2020 Jan 16;12(1):228. Dighriri IM, Alsubaie AM, Hakami et al. Effects of Omega-3 Polyunsaturated Fatty Acids on Brain Functions: A Systematic Review. Cureus. 2022 Oct 9;14(10):e30091 
  3. Andriambelo B, Stiffel M, Roke K, Plourde M. New perspectives on randomized controlled trials with omega-3 fatty acid supplements and cognition: A scoping review. Ageing Res Rev. 2023 Mar;85:101835. 
  4. Ramezani M, Meymand AZ, Khodagholi F, et al. A role for flavonoids in the prevention and/or treatment of cognitive dysfunction, learning, and memory deficits: a review of preclinical and clinical studies. Nutr Neurosci. 2023 Feb;26(2):156-172.
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