์ด ์„ธ์…˜์— ๋Œ€ํ•œ ๊ธฐ๋ณธ ์„ค์ •์ด ์—…๋ฐ์ดํŠธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๊ณ ๊ฐ๋‹˜์˜ ๊ณ„์ • ์„ค์ •์„ ์˜๊ตฌ์ ์œผ๋กœ ๋ณ€๊ฒฝํ•˜๋ ค๋ฉด ๋‚ด ๊ณ„์ •์œผ๋กœ ์ด๋™ํ•˜์„ธ์š”.
์›ํ•˜๋Š” ์ˆ˜๋ น ๊ตญ๊ฐ€ ๋˜๋Š” ์‚ฌ์šฉ ์–ธ์–ด๋ฅผ ๋‚ด ๊ณ„์ •์—์„œ ์–ธ์ œ๋“ ์ง€ ์—…๋ฐ์ดํŠธํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.
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다낭성 난소 증후군(PCOS)의 자연 치료법

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ํ”ํžˆ PCOS๋ผ๊ณ  ๋ถ€๋ฅด๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(Polycystic ovarian syndrome)์€ ์ „ ์„ธ๊ณ„ 16์„ธ์—์„œ 45์„ธ ์‚ฌ์ด ์—ฌ์„ฑ์˜ ์ตœ๋Œ€ 10ํผ์„ผํŠธ์— ํ•ด๋‹นํ•˜๋Š” ์ธ๊ตฌ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜๋Š” ์งˆ๋ณ‘์ž…๋‹ˆ๋‹ค. ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS) ์งˆํ™˜์„ ์•“๋Š” ์—ฌ์„ฑ์€ ์ธ์Š๋ฆฐ ํ˜ˆ๋‹น ์ˆ˜์น˜๊ฐ€ ์ •์ƒ๋ณด๋‹ค ๋†’๊ณ  ๊ณผ์ฒด์ค‘ ํ˜„์ƒ์„ ๋ณด์—ฌ ์‹ ์ฒด์— ๋‹ค์–‘ํ•œ ํ˜ธ๋ฅด๋ชฌ ๋ณ€ํ™”๋ฅผ ์ผ์œผํ‚ด์œผ๋กœ ๊ณผ๋„ํ•œ ๋ชจ๋ฐœ ์ƒ์žฅ๊ณผ ์—ฌ๋“œ๋ฆ„, ์ƒ๋ฆฌ๋ถˆ์ˆœ๊ณผ ๋‚œ์ž„ ๋“ฑ์„ ์ดˆ๋ž˜ํ•ฉ๋‹ˆ๋‹ค.

์›์ธ

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์˜ ๋ฐœ์ƒ ์›์ธ์€ ๋‹ค์–‘ํ•ฉ๋‹ˆ๋‹ค. ์ฒซ์งธ, ๊ฐ€๊ณต์‹ํ’ˆ๊ณผ ์„คํƒ•, ํ”„๋ฃฉํ† ์ฆˆ ํ•จ๋Ÿ‰์ด ๋†’์€ ์ฝ˜ ์‹œ๋Ÿฝ๊ณผ ์ฝœ๋ผ, ๊ทธ๋ฆฌ๊ณ  ๋‹จ์ˆœ ํฌ๋„๋‹น์˜ ๊ณผ๋„ํ•œ ์„ญ์ทจ๋Š” ์ฒด์ค‘ ์ฆ๊ฐ€์˜ ์›์ธ์œผ๋กœ ๊ผฝํž™๋‹ˆ๋‹ค. ์ด๋Š” ์ธ์Š๋ฆฐ ์ €ํ•ญ์„ฑ๊ณผ ๊ธฐํƒ€ ๋ณ€ํ™”๋ฅผ ์ดˆ๋ž˜ํ•˜์—ฌ ํ˜ธ๋ฅด๋ชฌ๊ณผ ๋‚ด๋ถ„๋น„๊ณ„์— ์˜ํ–ฅ์„ ๋ฏธ์ณ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS) ๋ฐœ์ƒ์„ ์ดˆ๋ž˜ํ•ฉ๋‹ˆ๋‹ค. ๋‹น๋‡จ๋ณ‘ ์ „์ฆ(Pre-diabetes)๊ณผ ํ˜ˆ๋‹น๋Ÿ‰ ์ฆ๊ฐ€ ์—ญ์‹œ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์˜ ์›์ธ์ด๋ผ๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์˜ ๋˜ ๋‹ค๋ฅธ ์›์ธ์œผ๋กœ๋Š” ๋ชจ๋“  ์—ฌ์„ฑ์—๊ฒŒ์„œ ์ตœ๋Œ€ 10ํผ์„ผํŠธ๊นŒ์ง€ ๋ฐœ์ƒํ•˜๋Š” ๊ฐ‘์ƒ์„  ๊ธฐ๋Šฅ ์ €ํ•˜์ฆ(Hypothyroidism)์ด ์žˆ์Šต๋‹ˆ๋‹ค. ๊ฐ‘์ƒ์„  ๊ธฐ๋Šฅ ์ €ํ•˜์ฆ์„ ์•“๋Š” ์—ฌ์„ฑ์˜ ๊ฒฝ์šฐ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์˜ ๋ฐœ๋ณ‘ ์œ„ํ—˜์ด ์ฆ๊ฐ€ํ•œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ํ™˜๊ฒฝ ๋…์„ฑ ์—ญ์‹œ ํ˜ธ๋ฅด๋ชฌ ์ด์ƒ์— ์˜ํ–ฅ์„ ๋ฏธ์น  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ํ”Œ๋ผ์Šคํ‹ฑ์— ํ•จ์œ ๋˜์–ด ์žˆ๋Š” ํ™”ํ•™ ๋ฌผ์งˆ์ธ ๋น„์ŠคํŽ˜๋†€ A ๋˜๋Š” BPA๊ฐ€ ์—ฌ์„ฑ์˜ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS) ๋ฐœ๋ณ‘๊ณผ ๊ด€๋ จ์ด ์žˆ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์˜ ์ฆ์ƒ

  • ์ดˆ์ŒํŒŒ์ƒ์— ๋‚˜ํƒ€๋‚˜๋Š” ๋‹ค์ˆ˜์˜ ๋‚œ์†Œ ๋‚ญ์ข…
  • ์–ผ๊ตด๊ณผ ๊ฐ€์Šด ๋“ฑ์˜ ๊ณผ๋„ํ•œ ์ฒด๋ชจ ์ƒ์žฅ
  • ์ƒ๋ฆฌ๋ถˆ์ˆœ
  • ๋‚œ์ž„
  • ์—ฌ๋“œ๋ฆ„
  • ๋น„๋งŒ
  • ์ง€๋ฐฉ๊ฐ„
  • ๊ณผ๋ฏผ์„ฑ ๋Œ€์žฅ ์ฆ์ƒ(IBS)
  • ๋‚จ์„ฑ์  ํƒˆ๋ชจ
  • ์ธ์Š๋ฆฐ ์ €ํ•ญ์„ฑ
  • ๋‹น๋‡จ๋ณ‘ ์ „์ฆ
  • ์ž๊ฐ€ ๋ฉด์—ญ ๊ฐ‘์ƒ์„  ์งˆ๋ณ‘ ์œ„ํ—˜ ์ฆ๊ฐ€
  • ํ˜ˆ์•ก ๊ฒ€์‚ฌ์ƒ ๋‚˜ํƒ€๋‚˜๋Š” ํ…Œ์Šคํ† ์Šคํ…Œ๋ก , LH ๋Œ€ FSH ๋น„์œจ ์ฆ๊ฐ€

์ง„๋‹จ

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์€ ์œ„ ์ฆ์ƒ์„ ๊ธฐ์ดˆ๋กœ ์˜์‚ฌ๊ฐ€ ์ž„์ƒ์ ์œผ๋กœ ์ง„๋‹จํ•ฉ๋‹ˆ๋‹ค. ์˜์‚ฌ์˜ ์ง„๋‹จ ๊ฒฐ๊ณผ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์ด ์˜์‹ฌ๋˜๋ฉด ์ถ”๊ฐ€ ํ™•์ธ๊ณผ ์ •ํ™•ํ•œ ์งˆ๋ณ‘ ํŒŒ์•…์„ ์œ„ํ•ด ์ž„์ƒ ๊ฒ€์‚ฌ์™€ ์ดˆ์ŒํŒŒ ๊ฒ€์‚ฌ๋ฅผ ์‹ค์‹œํ•  ๊ฒƒ์ž…๋‹ˆ๋‹ค.

์ƒํ™œ ์Šต๊ด€์˜ ๋ณ€ํ™”

์ƒํ™œ ์Šต๊ด€์„ ๋ณ€ํ™”์‹œํ‚ค๋ฉด ํ˜ธ๋ฅด๋ชฌ ๊ท ํ˜•๊ณผ ์‹ ์ง„๋Œ€์‚ฌ์˜ ๊ท ํ˜• ํšŒ๋ณต์— ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค. ๋‹ค์Œ๊ณผ ๊ฐ™์€ ์ƒํ™œ ์Šต๊ด€์˜ ๋ณ€ํ™”๊ฐ€ ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค.

  • ์ฒด์ค‘ ๊ฐ๋Ÿ‰ – ์ ์ ˆํ•œ ์ฒด์ค‘์œผ๋กœ ๊ฐ๋Ÿ‰ํ•  ๊ฒฝ์šฐ, ํ˜ธ๋ฅด๋ชฌ ๊ท ํ˜•์ด ์ฆ์ง„๋ฉ๋‹ˆ๋‹ค.
  • ์ผ์ƒ์ ์ธ ์šด๋™, ์ค‘๊ฐ„ ๊ฐ•๋„๋กœ ์‹ค์‹œํ•˜๋Š” ์ตœ์†Œ 30๋ถ„๊ฐ„์˜ ์šด๋™์„ ์ฃผ 5ํšŒ ์‹ค์‹œํ•˜๋ฉด ์ข‹์Šต๋‹ˆ๋‹ค.
  • ์ฑ„์†Œ์™€ ๊ณผ์ผ์ด ํ’๋ถ€ํ•œ ์‹๋‹จ ์„ญ์ทจ
  • ์‹๋‹จ๊ณผ ํ”„๋กœ๋ฐ”์ด์˜คํ‹ฑ์Šค ์„ญ์ทจ๋ฅผ ํ†ตํ•œ ์žฅ ๊ฑด๊ฐ•์˜ ์ตœ์ ํ™”
  • ํŒ”๋ ˆ์˜ค ์‹๋‹จ, ์ผ€ํ†  ๋‹ค์ด์–ดํŠธ ๋˜๋Š” ์ง€์ค‘ํ•ด ์‹๋‹จ์ด ์ตœ์ ์˜ ์ฒด์ค‘ ๊ฐ๋Ÿ‰์— ๋„์›€์ด ๋œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

์•ฝ๋ฌผ์น˜๋ฃŒ

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์œผ๋กœ ์ง„๋‹จ๋ฐ›๋Š” ๊ฒฝ์šฐ, ์˜์‚ฌ๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์˜ ์˜ํ–ฅ์„ ๊ฐ์†Œ์‹œํ‚ค๊ณ  ์‹ ์ง„๋Œ€์‚ฌ์™€ ํ˜ธ๋ฅด๋ชฌ ๊ท ํ˜•์„ ๊ฐœ์„ ํ•˜๊ธฐ ์œ„ํ•˜์—ฌ ์•ฝ๋ฌผ์„ ์ฒ˜๋ฐฉํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์ด๋•Œ ๊ฐ€์žฅ ๋งŽ์ด ์ฒ˜๋ฐฉํ•˜๋Š” ์•ฝ๋ฌผ์€ ๋‹ค์Œ๊ณผ ๊ฐ™์Šต๋‹ˆ๋‹ค.

๋ฉ”ํŠธํฌ๋ฏผ(Metformin) – ๋‹น๋‡จ๋ณ‘ ์น˜๋ฃŒ์— ์ž์ฃผ ์ด์šฉ๋˜๋Š” ๋ฉ”ํŠธํฌ๋ฏผ์€ ์ธ์ฒด์—์„œ ์ƒ์‚ฐ๋˜๋Š” ์ธ์Š๋ฆฐ์ด ๋”์šฑ ํšจ์œจ์ ์œผ๋กœ ์‚ฌ์šฉ๋˜๋„๋ก ํ•ฉ๋‹ˆ๋‹ค. ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ๋Œ€๋ถ€๋ถ„์ด ์ธ์Š๋ฆฐ ์ €ํ•ญ์„ฑ์„ ๋ณด์ž…๋‹ˆ๋‹ค. ๋ฉ”ํŠธํฌ๋ฏผ์€ ์ด๋Ÿฌํ•œ ์—ฌ์„ฑ์˜ ์ƒ๋ฆฌ ์ฃผ๊ธฐ๋ฅผ ์ •์ƒ์œผ๋กœ ํšŒ๋ณต์‹œํ‚ค๋Š” ๋ฐ ๋„์›€์ด ๋ฉ๋‹ˆ๋‹ค.

ํด๋กœ๋ฏธํŽœ(Clomiphene) – ํด๋กœ๋ฏธํŽœ์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ๋ฐฐ๋ž€๊ณผ ์ž„์‹ ์— ๋„์›€์„ ์ค๋‹ˆ๋‹ค.

๊ฒฝ๊ตฌ ํ”ผ์ž„์•ฝ(Oral Contraceptives) – ๊ฒฝ๊ตฌ ํ”ผ์ž„์•ฝ์€ ์›”๊ฒฝ ์ฃผ๊ธฐ ์กฐ์ ˆ๊ณผ ํ˜ธ๋ฅด๋ชฌ ๊ท ํ˜•์— ์ž์ฃผ ์‚ฌ์šฉ๋ฉ๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ๊ฒฝ๊ตฌ ํ”ผ์ž„์•ฝ์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์„ ์น˜๋ฃŒํ•˜์ง€๋Š” ๋ชปํ•ฉ๋‹ˆ๋‹ค.

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์— ์ข‹์€ ์ฒœ์—ฐ ๊ฑด๊ฐ• ๋ณด์กฐ์ œ

์‹๋‹จ๊ณผ ์ƒํ™œ ์Šต๊ด€์˜ ๋ณ€ํ™”๋ฅผ ํ†ตํ•ด ์—ฌ์„ฑ์˜ ์‹ ์ง„๋Œ€์‚ฌ์™€ ํ˜ธ๋ฅด๋ชฌ ๊ท ํ˜•์„ ์ •์ƒ์œผ๋กœ ํšŒ๋ณตํ•˜๋Š” ๋ฐฉ๋ฒ• ์™ธ์—๋„ ๊ฑด๊ฐ• ์œ ์ง€๋ฅผ ์œ„ํ•ด ๋ณด์กฐ์ œ๋ฅผ ์„ญ์ทจํ•˜๋Š” ๋ถ„์ด ๋งŽ์Šต๋‹ˆ๋‹ค. ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์น˜๋ฃŒ๋ฅผ ์œ„ํ•œ ์ฒ˜๋ฐฉ ์•ฝ๋ฌผ๊ณผ ํ•จ๊ป˜ ์„ญ์ทจํ•  ์ˆ˜ ์žˆ๋Š” ๋ณด์กฐ์ œ๋Š” ๋‹ค์Œ๊ณผ ๊ฐ™์Šต๋‹ˆ๋‹ค.

๋น„ํƒ€๋ฏผ D

์ „ ์„ธ๊ณ„ ์—ฌ์„ฑ์˜ 5๋ช… ์ค‘ ๊ฑฐ์˜ 4 ๋ช…๊ผด๋กœ ๋น„ํƒ€๋ฏผ D ๊ฒฐํ•์ฆ์„ ๋ณด์ž…๋‹ˆ๋‹ค. ๋น„ํƒ€๋ฏผ D๋Š” “ํ–‡๋ณ• ๋น„ํƒ€๋ฏผ”์œผ๋กœ๋„ ์ž˜ ์•Œ๋ ค์ ธ ์žˆ์Šต๋‹ˆ๋‹ค. ๋น„ํƒ€๋ฏผ D ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์€ ๊ฒฝ์šฐ, ๋‹ค์–‘ํ•œ ์งˆ๋ณ‘์— ๊ฑธ๋ฆด ์œ„ํ—˜์ด ๋†’์Šต๋‹ˆ๋‹ค.  

์œ„์— ์–ธ๊ธ‰ํ•œ ๋ฐ”์™€ ๊ฐ™์ด ์ง€๋ฐฉ๊ฐ„์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์—๊ฒŒ ํ”ํžˆ ๋‚˜ํƒ€๋‚˜๋Š” ์ฆ์ƒ์ž…๋‹ˆ๋‹ค. 2017๋…„์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ๋น„ํƒ€๋ฏผ D๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์งˆํ™˜์— ๊ฑธ๋ฆฐ ๊ณผ์ฒด์ค‘ ์—ฌ์„ฑ์˜ ์ง€๋ฐฉ๊ฐ„ ํ‘œ์ง€ ๋ฌผ์งˆ์„ ๊ฐ์†Œ์‹œํ‚ค๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. 2016๋…„ ๋‚ด๋ถ„๋น„ ๋ฐ ์‹ ์ง„๋Œ€์‚ฌ ์ž„์ƒํ•™ํšŒ์ง€(Journal Of Clinical Endocrinology and Metabolism)์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ, ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์ง„๋‹จ์„ ๋ฐ›์€ ์—ฌ์„ฑ์˜ 44ํผ์„ผํŠธ๊ฐ€ ๋น„ํƒ€๋ฏผ D ์ˆ˜์น˜๊ฐ€ 30 ng/ml (75 nmol/L) ๋ฏธ๋งŒ์ผ ๊ฒฝ์šฐ ํ˜ˆ์ค‘ ๋น„ํƒ€๋ฏผ D ์ˆ˜์น˜๊ฐ€ ๋†’์€ ์—ฌ์„ฑ์— ๋น„ํ•ด ์ž„์‹  ๊ฐ€๋Šฅ์„ฑ์ด ๋‚ฎ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

๋งˆ์ง€๋ง‰์œผ๋กœ, ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์ง„๋‹จ์„ ๋ฐ›์€ ์—ฌ์„ฑ์˜ ๊ฒฝ์šฐ, ์ž๊ฐ€ ๋ฉด์—ญ ๊ฐ‘์ƒ์„  ์—ผ์ฆ์˜ ๋ฐœ์ƒ ์œ„ํ—˜์ด ์ฆ๊ฐ€ํ•˜๋ฏ€๋กœ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์„ ์‚ฌ์ „์— ์˜ˆ๋ฐฉํ•˜๋Š” ๊ฒƒ์ด ๋งค์šฐ ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. 2016๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์ง„๋‹จ์„ ๋ฐ›์€ ์—ฌ์„ฑ์—๊ฒŒ์„œ ๋น„ํƒ€๋ฏผ D ๊ฒฐํ•์ฆ์ด ๋ฐœ์ƒํ•  ๊ฒฝ์šฐ, ์ž๊ฐ€ ๋ฉด์—ญ ๊ฐ‘์ƒ์„  ์งˆํ™˜์œผ๋กœ ๋ฐœ์ „ํ•  ์œ„ํ—˜์ด ์ฆ๊ฐ€ํ•œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰: ๋งค์ผ 1,000-5,000IU

ํฌ๋กœ๋ฏธ์›€

ํฌ๋กœ๋ฏธ์›€์€ ํฌ๋„๋‹น ๋‚ด์„ฑ ์ธ์ž(glucose tolerance factor, GTF) ํšจ์†Œ๋ฅผ ๋น„๋กฏํ•œ ์ˆ˜๋งŽ์€ ํšจ์†Œ ๋ฐ˜์‘์— ํ•„์š”ํ•œ ์ฃผ์š” ๋ฌผ์งˆ์ž…๋‹ˆ๋‹ค. ํฌ๋„๋‹น ๋‚ด์„ฑ ์ธ์ž ํšจ์†Œ๋Š” ์ธ์Š๋ฆฐ ๊ธฐ๋Šฅ๊ณผ ํฌ๋„๋‹น ์กฐ์ ˆ์— ๊ธฐ์—ฌํ•˜๋Š” ํšจ์†Œ์ž…๋‹ˆ๋‹ค.

2017๋…„, ์˜ํ•™ ๋ฐ ์ƒ๋ฌผํ•™ ๋ฏธ๋Ÿ‰ ์›์†Œ ํ•™ํšŒ์ง€(Journal of Trace Elements in Medicine and Biology)์— ๋ฐœํ‘œ๋œ ๋ฉ”ํƒ€ ๋ถ„์„ ์—ฐ๊ตฌ๋Š” ํฌ๋กœ๋ฏธ์›€ ํ”ผ์ฝœ๋ฆฌ๋„ค์ดํŠธ(Chromium picolinate)๋ฅผ ์„ญ์ทจํ•  ๊ฒฝ์šฐ ์ฒด์งˆ๋Ÿ‰ ์ง€์ˆ˜(BMI)๋ฅผ ๊ฐ์†Œ์‹œํ‚ค๊ณ , ๊ณต๋ณต ์ธ์Š๋ฆฐ ์ˆ˜์น˜๋ฅผ ๋‚ฎ์ถ”๋ฉฐ, ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก  ์ˆ˜์น˜๋ฅผ ๋‚ฎ์ถ˜๋‹ค๋Š” ๊ฒฐ๋ก ">๊ฒฐ๋ก ์„ ๋‚ด๋ฆฌ๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ์ธ์Š๋ฆฐ ์ˆ˜์น˜์˜ ์ฆ๊ฐ€๋Š” ์ง€๋ฐฉ ์ถ•์  ๋ฐ ์ฒด์ค‘ ์ฆ๊ฐ€์™€ ๊ด€๋ จ์ด ์žˆ์Šต๋‹ˆ๋‹ค.

๋งˆ์ฐฌ๊ฐ€์ง€๋กœ, 2015๋…„ ์˜์–‘ํ•™ ๋ฐ ์‹ ์ง„๋Œ€์‚ฌ ์—ฐ๋ณด(Annals of Nutrition and Metabolism)์— ๋ฐœํ‘œ๋œ ์ด์ค‘ ๋งน๊ฒ€, ์œ„์•ฝ ์กฐ์ ˆ ์ž„์ƒ ์‹œํ—˜ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ํฌ๋กœ๋ฏธ์›€์˜ ์„ญ์ทจ๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ์ธ์Š๋ฆฐ ์ˆ˜์น˜๋ฅผ ๋‚ฎ์ถ”๊ณ  ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๋ฅผ ๊ฐœ์„ ํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ 2018๋…„์— ๋ฐœํ‘œํ•œ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ํฌ๋กœ๋ฏธ์›€ ์„ญ์ทจ๊ฐ€ ๋šœ๋ ทํ•œ ๊ฐœ์„  ํšจ๊ณผ๋ฅผ ๋ณด์ด์ง€ ์•Š๋Š”๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ๋”ฐ๋ผ์„œ ์ด์— ๊ด€ํ•˜์—ฌ ๋”์šฑ ๋งŽ์€ ์—ฐ๊ตฌ๊ฐ€ ํ•„์š”ํ•œ ์‹ค์ •์ž…๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰: 200mg์”ฉ 1์ผ 1-2ํšŒ ๋ณต์šฉ

N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ(NAC)

N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ(NAC)์€ ์ธ์ฒด ํ•ด๋… ์ž‘์šฉ์— ๊ด€์—ฌํ•˜๋Š” ์ค‘์š” ์˜์–‘์†Œ์ž…๋‹ˆ๋‹ค. N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ์€ ์•„์„ธํŠธ ์•„๋ฏธ๋…ธํŽœ/ํŒŒ๋ผ์„ธํƒ€๋ชฐ(ํƒ€์ด๋ ˆ๋†€) ๊ณผ๋‹ค ๋ณต์šฉ์œผ๋กœ ์ž…์›ํ•œ ํ™˜์ž์—๊ฒŒ ์ฒ˜๋ฐฉํ•˜๋Š” ์•ฝ๋ฌผ์ž…๋‹ˆ๋‹ค.

2015๋…„ ๊ตญ์ œ ์‚ฐ๋ถ€์ธ๊ณผ ํ•™ํšŒ์ง€(Obstetrics and Gynecology International)์— ๋ฐœํ‘œ๋œ ๋ฉ”ํƒ€ ๋ถ„์„์— ๋”ฐ๋ฅด๋ฉด ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์ด N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ์„ ๋ณต์šฉํ•  ๊ฒฝ์šฐ ๋ฐฐ๋ž€์ด ์ด‰์ง„๋˜๋ฏ€๋กœ ์œ„์•ฝ์„ ๋ณต์šฉํ•œ ์—ฌ์„ฑ์— ๋น„ํ•ด ์ž„์‹ ์ด ์šฉ์ดํ•ด์ง€๊ณ  ์ถœ์‚ฐ์—๋„ ๋„์›€์ด ๋œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ์˜ ๋ณต์šฉ์€ ์—ฌ์„ฑ์—๊ฒŒ ๋šœ๋ ทํ•œ ๋ถ€์ž‘์šฉ์„ ์ผ์œผํ‚ค์ง€ ์•Š์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ 2015๋…„์—๋Š” N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ 600 mg์„ 1์ผ 3ํšŒ ๋ณต์šฉํ•œ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์„ ๋ฉ”ํŠธํฌ๋ฏผ 500 mg์„ 1์ผ 3ํšŒ ๋ณต์šฉํ•œ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ๊ณผ ๋น„๊ตํ•œ ์—ฐ๊ตฌ๊ฐ€ ๋ฐœํ‘œ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ์—ฐ๊ตฌ ๊ฒฐ๊ณผ, N-์•„์„ธํ‹ธ ์‹œ์Šคํ…Œ์ธ์€ ์˜์•ฝํ’ˆ์ธ ๋ฉ”ํƒ€ํฌ๋ฏผ์— ๋น„ํ•ด ๊ณต๋ณต ํ˜ˆ๋‹น๋Ÿ‰๊ณผ ์ฝœ๋ ˆ์Šคํ…Œ๋กค ๊ฐ•ํ•˜ ํšจ๊ณผ๊ฐ€ ํƒ์›”ํ•œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

L-์นด๋ฅด๋‹ˆํ‹ด

L-์นด๋ฅด๋‹ˆํ‹ด(Carnitine)์€ ๊ทผ์œก๊ณผ ๋‘๋‡Œ์— ๊ณ ๋†๋„๋กœ ์กด์žฌํ•˜๋Š” ์ค‘์š”ํ•œ ์•„๋ฏธ๋…ธ์‚ฐ์ž…๋‹ˆ๋‹ค. ์ด๋Š” ๋˜ํ•œ ์—๋„ˆ์ง€ ์ƒ์‚ฐ๊ณผ ์‹ ์ง„๋Œ€์‚ฌ์—๋„ ์ค‘์š”ํ•œ ์—ญํ• ์„ ๋ฐœํœ˜ํ•ฉ๋‹ˆ๋‹ค. 2015๋…„์—๋Š” 60๋ช…์˜ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ ํ™˜์ž๋ฅผ ๋Œ€์ƒ์œผ๋กœ ํ•˜๋Š” ๋ฌด์ž‘์œ„, ์ด์ค‘ ๋งน๊ฒ€, ์œ„์•ฝ ์กฐ์ ˆ ์ž„์ƒ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๊ฐ€ ๋ฐœํ‘œ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ์—ฐ๊ตฌ์— ์ฐธ์—ฌํ•œ ๋ชจ๋“  ์ž„์ƒ ์‹œํ—˜ ๋Œ€์ƒ์ž๋Š” ๊ณผ์ฒด์ค‘์ด์—ˆ์Šต๋‹ˆ๋‹ค. ์ด ์ค‘, ์ ˆ๋ฐ˜์— ํ•ด๋‹นํ•˜๋Š” ์ž„์ƒ ์‹œํ—˜ ๋Œ€์ƒ์ž์—๊ฒŒ๋Š” 250 mg์˜ L-์นด๋ฅด๋‹ˆํ‹ด์„ ๋ณต์šฉํ•˜๋„๋ก ํ•˜์˜€๊ณ , ๋‚˜๋จธ์ง€ 30๋ช…์˜ ์—ฌ์„ฑ์—๊ฒŒ๋Š” ์œ„์•ฝ์„ ์ฒ˜๋ฐฉํ•˜์˜€์Šต๋‹ˆ๋‹ค. ์ด ๋‘ ์‹œํ—˜๊ตฐ์„ 12์ฃผ ๋™์•ˆ ์ถ”์ ํ•˜์—ฌ ์กฐ์‚ฌํ•œ ๊ฒฐ๊ณผ, ์นด๋ฅด๋‹ˆํ‹ด์„ ๋ณต์šฉํ•œ ์—ฌ์„ฑ์€ ์—ฐ๊ตฌ ์ข…๋ฃŒ ์‹œ ์ฒด์ค‘๊ณผ ํ—ˆ๋ฆฌ๋‘˜๋ ˆ๊ฐ€ ์ค„์–ด๋“ค์—ˆ๋‹ค๋Š” ์‚ฌ์‹ค๊ณผ ํ•จ๊ป˜ ํ˜ˆ๋‹น๋Ÿ‰์ด ๊ฐ์†Œํ•œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

2014๋…„ ์œ ๋Ÿฝ ์‚ฐ๋ถ€์ธ๊ณผ ๋ฐ ์ƒ์‹ ์ƒ๋ฌผํ•™ ํ•™ํšŒ์ง€(European Journal of Obstetrics and Gynecology and Reproductive Biology)์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ์—์„œ๋Š” (ํด๋กœ๋ฏธํŽœ ์•ฝ๋ฌผ์ด ์ž„์‹ ์— ์˜ํ–ฅ์„ ๋ฏธ์น˜์ง€ ๋ชปํ•˜๋Š”) ํด๋กœ๋ฏธํŽœ ์ €ํ•ญ์„ฑ ํ™˜์ž๊ฐ€ ์ผ์ƒ์ ์ธ ์•ฝ๋ฌผ ์น˜๋ฃŒ์˜ ์ผํ™˜์œผ๋กœ 3000 mg์˜ L-์นด๋ฅด๋‹ˆํ‹ด์„ ๋ณต์šฉํ•  ๋•Œ ์ž„์‹  ๊ฐ€๋Šฅ์„ฑ์ด ๋†’์•„์กŒ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ์ด๋Š” ๊ฑด๊ฐ• ์œ ์ง€๋ฅผ ์œ„ํ•˜์—ฌ ์ฒ˜๋ฐฉ ์•ฝ๋ฌผ๊ณผ ๊ฑด๊ฐ• ๋ณด์กฐ์ œ๋ฅผ ๋ณ‘์šฉํ•œ ์ข‹์€ ์˜ˆ์— ํ•ด๋‹นํ•ฉ๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰ : ํ•˜๋ฃจ 250 mg์—์„œ 3,000 mg

์ฝ”์—”์ž์ž„ Q10

์ฝ”์—”์ž์ž„ Q10์€ ์—๋„ˆ์ง€ ์‹ ์ง„๋Œ€์‚ฌ์— ์ค‘์š”ํ•œ ์—ญํ• ์„ ๋‹ด๋‹นํ•˜๋Š” ๋ณด์ถฉ์ œ์ž…๋‹ˆ๋‹ค. 2017๋…„, ์ž„์ƒ ๋‚ด๋ถ„๋น„ํ•™ํšŒ์—๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ 100 mg์˜ ์ฝ”์—”์ž์ž„ Q10์„ ์œ„์•ฝ๊ณผ ๋น„๊ตํ•˜์—ฌ ํ‰๊ฐ€ํ•˜๋Š” ์ด์ค‘ ๋งน๊ฒ€, ์œ„์•ฝ ์กฐ์ ˆ ์ž„์ƒ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๊ฐ€ ๋ฐœํ‘œ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ํ•ด๋‹น ์—ฐ๊ตฌ์—์„œ๋Š” ํ˜ˆ์•ก ๊ฒ€์‚ฌ๋ฅผ ์‹ค์‹œํ•œ ์ž„์ƒ ์—ฐ๊ตฌ ๋Œ€์ƒ์ž์—๊ฒŒ 12์ฃผ๊ฐ„ ์ฝ”์—”์ž์ž„ Q10์ด๋‚˜ ์œ„์•ฝ์„ ๋ณต์šฉํ•˜๋„๋ก ํ•œ ํ›„, ํ˜ˆ์•ก ๊ฒ€์‚ฌ๋ฅผ ๋‹ค์‹œ ์‹ค์‹œํ•˜์˜€์Šต๋‹ˆ๋‹ค. ์—ฐ๊ตฌ ๊ฒฐ๊ณผ, ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ํ™˜์ž์—๊ฒŒ์„œ ํ”ํžˆ ์ˆ˜์น˜๊ฐ€ ๋†’๊ฒŒ ๋‚˜ํƒ€๋‚˜๋Š” ํ˜ˆ๋‹น๋Ÿ‰๊ณผ ์ธ์Š๋ฆฐ ์ˆ˜์น˜๊ฐ€ ์ฝ”์—”์ž์ž„ Q10์„ ๋ณต์šฉํ•œ ์ž„์ƒ ์—ฐ๊ตฌ ๋Œ€์ƒ์ž์—๊ฒŒ์„œ๋Š” ๊ฐ์†Œํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. 2015๋…„์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ ์—ญ์‹œ ํด๋กœ๋ฏธํŽœ์— ์ €ํ•ญ์„ฑ์„ ๋ณด์ด๋Š” ํ™˜์ž๊ฐ€ ์ฝ”์—”์ž์ž„ Q10์„ ๋ณต์šฉํ•  ๊ฒฝ์šฐ ๋ฐฐ๋ž€๊ณผ ์ž„์‹ ์ด ์ด‰์ง„๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰: ํ•˜๋ฃจ 100 - 300 mg

์˜ค๋ฉ”๊ฐ€ 3- ์ง€๋ฐฉ์‚ฐ

์˜ค๋ฉ”๊ฐ€-3 ํ•„์ˆ˜ ์ง€๋ฐฉ์‚ฐ์€ ๊ธฐ๋ณธ์ ์œผ๋กœ ์—์ด์ฝ”์‚ฌํŽœํƒ€์—๋…ธ์‚ฐ(EPA)๊ณผ ๋„์ฝ”์‚ฌํ—ฅ์‚ฌ์—๋…ธ์‚ฐ(DHA)์œผ๋กœ ๊ตฌ์„ฑ๋˜์–ด ์žˆ์Šต๋‹ˆ๋‹ค. ์˜ค๋ฉ”๊ฐ€-3 ํ•„์ˆ˜ ์ง€๋ฐฉ์‚ฐ์€ (๊ณ ๋“ฑ์–ด, ๋Œ€๊ตฌ ๋ฐ ์—ฐ์–ด๋ฅผ ๋น„๋กฏํ•œ) ์ƒ์„ ๊ณผ ํ˜ธ๋‘, ์น˜์•„ ์”จ์•—, ์•„๋งˆ ์”จ์•—, ํ—ดํ”„ ์”จ์•—, ์•„๋ณด์นด๋„ ๋ฐ ๋‚˜ํ† ์™€ ๊ฐ™์€ ๋‹ค์–‘ํ•œ ์‹ํ’ˆ์— ํ’๋ถ€ํ•˜๊ฒŒ ํ•จ์œ ๋˜์–ด ์žˆ์Šต๋‹ˆ๋‹ค.

์ง€๋ฐฉ๊ฐ„์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์—๊ฒŒ์„œ ํ”ํžˆ ๋‚˜ํƒ€๋‚˜๋Š” ์ฆ์ƒ์ž…๋‹ˆ๋‹ค. 2009๋…„์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ์ง€๋ฐฉ๊ฐ„ ์ฆ์ƒ์„ ๋ณด์ด๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์ด ์˜ค๋ฉ”๊ฐ€-3 ์ง€๋ฐฉ์‚ฐ์„ ๋ณต์šฉํ•  ๊ฒฝ์šฐ ๊ฐ„ ์ง€๋ฐฉ์ด ๊ฐ์†Œํ•œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ํ•ด๋‹น ์—ฐ๊ตฌ์—์„œ ๋‚˜ํƒ€๋‚œ ํ˜ˆ์••๊ณผ ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ ๊ฐœ์„  ํšจ๊ณผ ์—ญ์‹œ ๋ˆˆ์—ฌ๊ฒจ๋ณผ๋งŒํ•œ ์ ์ž…๋‹ˆ๋‹ค. 2011๋…„์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ์—ญ์‹œ ์˜ค๋ฉ”๊ฐ€-3 ์ง€๋ฐฉ์‚ฐ์˜ ์„ญ์ทจ๊ฐ€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ์ƒ์ฒด ํ™œ์„ฑ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก  ๊ฐ•ํ•˜์— ์˜ํ–ฅ์„ ๋ฏธ์นœ๋‹ค๋Š” ์‚ฌ์‹ค์„ ๋ณด์˜€์Šต๋‹ˆ๋‹ค. ์ƒ์ฒด ํ™œ์„ฑ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก  ์ˆ˜์น˜๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์—๊ฒŒ์„œ ๋†’๊ฒŒ ๋‚˜ํƒ€๋‚ฉ๋‹ˆ๋‹ค. 2018๋…„์— ๋ฐœํ‘œ๋œ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ์•„๋งˆ ์”จ์•— ์„ญ์ทจ๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ์˜ ์ธ์Š๋ฆฐ ์ˆ˜์น˜์™€ ์ธ์Š๋ฆฐ ์ €ํ•ญ์„ฑ ๊ฐ•ํ•˜์— ๋„์›€์ด ๋œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰ : 1 ์ผ 1,000 ~ 2,000 mg ์˜จ์Šค์”ฉ 1์ผ 1-2ํšŒ ์„ญ์ทจ

์…€๋ ˆ๋Š„

์…€๋ ˆ๋Š„์€ ์ธ์ฒด์— ์•„์ฃผ ์ ์€ ์–‘์ด ํ•„์š”ํ•œ ๋ฏธ๋Ÿ‰ ์›์†Œ ๋ฏธ๋„ค๋ž„์ž…๋‹ˆ๋‹ค. ํ„ฐํ‚ค ์—ฌ์„ฑ์„ ๋Œ€์ƒ์œผ๋กœ ํ•œ 2013๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์—ฌ์„ฑ๋Š” ์ •์ƒ ์—ฌ์„ฑ์— ๋น„ํ•ด ํ˜ˆ์ค‘ ์…€๋ ˆ๋Š„ ๋†๋„๊ฐ€ ๋‚ฎ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ์…€๋ ˆ๋Š„ ๊ฒฐํ•์ฆ์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์„ ์œ ๋ฐœํ•˜๊ณ  ํ˜ธ๋ฅด๋ชฌ ์ˆ˜์น˜ ์กฐ์ ˆ์— ์ค‘์š”ํ•œ ์—ญํ• ์„ ๋‹ด๋‹นํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋ณด์ž…๋‹ˆ๋‹ค. ์—ฐ๊ตฌ ๊ฒฐ๊ณผ, ์…€๋ ˆ๋Š„ ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์„ ๊ฒฝ์šฐ ํ™ฉ์ฒด ํ˜•์„ฑ ํ˜ธ๋ฅด๋ชฌ(LH)๊ณผ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก  ์ˆ˜์น˜๊ฐ€ ์ฆ๊ฐ€ํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ํ™ฉ์ฒด ํ˜•์„ฑ ํ˜ธ๋ฅด๋ชฌ(LH) ์ˆ˜์น˜์™€ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก  ์ˆ˜์น˜ ์ฆ๊ฐ€๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ์—์„œ ํ”ํžˆ ๋‚˜ํƒ€๋‚˜๋Š” ์ฆ์ƒ์ž…๋‹ˆ๋‹ค.

2014๋…„์— ๋ฐœํ‘œ๋œ ๋ฌด์ž‘์œ„, ์ด์ค‘ ๋งน๊ฒ€, ์œ„์•ฝ ์กฐ์ ˆ ์ž„์ƒ ์—ฐ๊ตฌ์—์„œ ์…€๋ ˆ๋Š„์€ ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ ์น˜๋ฃŒ์— ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์Œ์ด ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. ํŠนํžˆ ์…€๋ ˆ๋Š„์€ ์ธ์Š๋ฆฐ ์ˆ˜์น˜๋ฅผ ๋‚ฎ์ถ”๊ณ  ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ ์ˆ˜์น˜ ๋ฐ LDL (๋‚˜์œ) ์ฝœ๋ ˆ์Šคํ…Œ๋กค์„ ๊ฐ•ํ•˜์‹œํ‚ค๋Š” ๋“ฑ, ์ฝœ๋ ˆ์Šคํ…Œ๋กค ๋น„์œจ์„ ๊ฐœ์„ ํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.

๊ถŒ์žฅ ๋ณต์šฉ๋Ÿ‰ : ๋งค์ผ 200 mcg (๋ณ„๋„์˜ ๋ณด์ถฉ์ œ๋กœ ๋ณต์šฉํ•˜๊ฑฐ๋‚˜ ๋Œ€๋ถ€๋ถ„์˜ ์ข…ํ•ฉ ๋น„ํƒ€๋ฏผ์— ํ•จ์œ ๋˜์–ด ์žˆ์Šต๋‹ˆ๋‹ค.)

๊ฒฐ๋ก 

๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(Polycystic Ovarian Syndrome, PCOS)์€ ๊ฐ€์ž„๊ธฐ ์—ฌ์„ฑ์ด ํ”ํžˆ ๊ฑธ๋ฆฌ๋Š” ์งˆํ™˜์ž…๋‹ˆ๋‹ค. ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)๋Š” ํ˜ธ๋ฅด๋ชฌ ๋ถˆ๊ท ํ˜•๊ณผ ์ƒ๋ฆฌ๋ถˆ์ˆœ์„ ์œ ๋ฐœํ•˜์—ฌ ๋‚œ์ž„์„ ์ดˆ๋ž˜ํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์‹๋‹จ๊ณผ ์ƒํ™œ ์Šต๊ด€์˜ ๋ณ€ํ™”๋Š” ๋‹ค๋‚ญ์„ฑ ๋‚œ์†Œ ์ฆํ›„๊ตฐ(PCOS)์˜ ์ฆ์ƒ์„ ํšŒ๋ณตํ•˜๋Š”๋ฐ ๊ฒฐ์ •์ ์ž…๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์‹๋‹จ๊ณผ ์ƒํ™œ ์Šต๊ด€์˜ ๋ณ€ํ™”๋งŒ์œผ๋กœ๋Š” ์ถฉ๋ถ„์น˜ ์•Š์„ ๊ฒฝ์šฐ ์ฒ˜๋ฐฉ์„ ํ†ตํ•œ ์•ฝ๋ฌผ์น˜๋ฃŒ์™€ ํŠน์ • ๋ณด์กฐ์ œ์˜ ๋ณต์šฉ์„ ๊ณ ๋ คํ•ด ๋ณผ ์ˆ˜ ์žˆ์œผ๋ฉฐ, ํšจ๊ณผ์  ์น˜๋ฃŒ๋ฅผ ์œ„ํ•ด ๋‘ ๊ฐ€์ง€๋ฅผ ๋ณ‘ํ–‰ํ•  ์ˆ˜๋„ ์žˆ์Šต๋‹ˆ๋‹ค.

์ฐธ๊ณ ๋ฌธํ—Œ:

  1. Eleni Kandaraki, Antonis Chatzigeorgiou, et. al Endocrine Disruptors and Polycystic Ovary Syndrome (PCOS): Elevated Serum Levels of Bisphenol A in Women with PCOS, The Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 3, 1 March 2011, Pages E480–E484,
  2. Endocrine Abstracts (2017) 50 P323 | DOI: 10.1530/endoabs.50.P323
  3. Lubna Pal, Heping Zhang, Joanne Williams, Nanette F. Santoro, et. al.  Vitamin D Status Relates to Reproductive Outcome in Women With Polycystic Ovary Syndrome: Secondary Analysis of a Multicenter Randomized Controlled Trial, The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 8, 1 August 2016, Pages 3027–3035, https://doi.org/10.1210/jc.2015-4352
  4. Siavash Fazelian, Mohamad H. Rouhani, Sahar Saraf Bank, Reza Amani, Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis, Journal of Trace Elements in Medicine and Biology, Volume 42, 2017, Pages 92-96, ISSN 0946-672X, https://doi.org/10.1016/j.jtemb.2017.04.008.
  5. Jamilian M, Asemi Z, Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab 2015;67:42-48
  6. Site Accessed September 5th, 2018  https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1111/jog.13462
  7. Divyesh Thakker, Amit Raval, Isha Patel, and Rama Walia, “N-Acetylcysteine for Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials,” Obstetrics and Gynecology International, vol. 2015, Article ID 817849, 13 pages, 2015. https://doi.org/10.1155/2015/817849.
  8. Forough Javanmanesh, Maryam Kashanian, Maryam Rahimi & Narges Sheikhansari (2016) A comparison between the effects of metformin and N-acetyl cysteine (NAC) on some metabolic and endocrine characteristics of women with polycystic ovary syndrome, Gynecological Endocrinology, 32:4, 285-289, DOI: 10.3109/09513590.2015.1115974
  9. Samimi, M. , Jamilian, M. , Ebrahimi, F. A., Rahimi, M. , Tajbakhsh, B. and Asemi, Z. (2016), Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, doubleโ€blind, placeboโ€controlled trial. Clin Endocrinol, 84: 851-857. doi:10.1111/cen.13003
  10. Alaa M. Ismail, Ali Hassan Hamed, Srdjan Saso, Hossam H. Thabet,  Adding l-carnitine to clomiphene resistant PCOS women improves the quality of ovulation and the pregnancy rate. A randomized clinical trial, European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 180, 2014, Pages 148-152, https://doi.org/10.1016/j.ejogrb.2014.06.008.
  11. Samimi, M. , Zarezade Mehrizi, M. , Foroozanfard, F. (2017), The effects of coenzyme Q10 supplementation on glucose metabolism and lipid profiles in women with polycystic ovary syndrome: a randomized, doubleโ€blind, placeboโ€controlled trial. Clin Endocrinol, 86: 560-566. doi:10.1111/cen.13288
  12. Abdelaziz El Refaeey, Amal Selem, Ahmed Badawy, Combined coenzyme Q10 and clomiphene citrate for ovulation induction in clomiphene-citrate-resistant polycystic ovary syndrome, Reproductive BioMedicine Online, Volume 29, Issue 1, 2014, Pages 119-124, ISSN 1472-6483, https://doi.org/10.1016/j.rbmo.2014.03.011.
  13. The Journal of Clinical Endocrinology & Metabolism, Volume 94, Issue 10, 1 October 2009, Pages 3842–3848, https://doi.org/10.1210/jc.2009-
  14. Niamh Phelan, Annalouise O’Connor. Hormonal and metabolic effects of polyunsaturated fatty acids in young women with polycystic ovary syndrome: results from a cross-sectional analysis and a randomized, placebo-controlled, crossover trial–, The American Journal of Clinical Nutrition, Volume 93, Issue 3, 1 March 2011, Pages 652 662,  https://doi.org/10.3945/ajcn.110.005538
  15. Exp Clin Endocrinol Diabetes 2018; 126(04): 222-228
  16. Jamilian, M. , Razavi, M. , Fakhrie Kashan, Z. , Ghandi, Y. , Bagherian, T. and Asemi, Z. (2015), Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, doubleโ€blind, placeboโ€controlled trial. Clin Endocrinol, 82: 885-891. doi:10.1111/cen.12699

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