์ด ์„ธ์…˜์— ๋Œ€ํ•œ ๊ธฐ๋ณธ ์„ค์ •์ด ์—…๋ฐ์ดํŠธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๊ณ ๊ฐ๋‹˜์˜ ๊ณ„์ • ์„ค์ •์„ ์˜๊ตฌ์ ์œผ๋กœ ๋ณ€๊ฒฝํ•˜๋ ค๋ฉด ๋‚ด ๊ณ„์ •์œผ๋กœ ์ด๋™ํ•˜์„ธ์š”.
์›ํ•˜๋Š” ์ˆ˜๋ น ๊ตญ๊ฐ€ ๋˜๋Š” ์‚ฌ์šฉ ์–ธ์–ด๋ฅผ ๋‚ด ๊ณ„์ •์—์„œ ์–ธ์ œ๋“ ์ง€ ์—…๋ฐ์ดํŠธํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.
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체력, 혈관 건강을 개선하는 L-아르기닌 및 L-시트룰린의 다양한 효능

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L-์•„๋ฅด๊ธฐ๋‹Œ์ด๋ž€?

L-์•„๋ฅด๊ธฐ๋‹Œ์€ ์ƒ์ฒ˜ ์น˜์œ , ๋””ํ†ก์Šค ๋ฐ˜์‘, ๋ฉด์—ญ ๊ธฐ๋Šฅ์— ์ค‘์š”ํ•œ ์—ญํ• ์„ ํ•˜๋Š” ์•„๋ฏธ๋…ธ์‚ฐ์œผ๋กœ ๊ธ€๋ฃจ์นด๊ณค(Glucagon), ์ธ์Š๋ฆฐ(Insulin), ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ์„ ๋น„๋กฏํ•œ ์—ฌ๋Ÿฌ ํ˜ธ๋ฅด๋ชฌ์˜ ๋ถ„๋น„๋ฅผ ์ด‰์ง„ํ•ฉ๋‹ˆ๋‹ค. 

๋˜ํ•œ L-์•„๋ฅด๊ธฐ๋‹Œ์€ ํ˜ˆ๊ด€์—์„œ ์‚ฐํ™”์งˆ์†Œ๊ฐ€ ํ˜•์„ฑ๋˜๋Š” ๋ฐ๋„ ์ค‘์š”ํ•œ ์—ญํ• ์„ ํ•ฉ๋‹ˆ๋‹ค. ์ฒด๋‚ด์—์„œ ์‚ฐํ™”์งˆ์†Œ๋Š” ํ˜ˆ๊ด€๊ธด์žฅ์„ ์กฐ์ ˆํ•˜๋Š” ๋ฐ ๊ด€์—ฌํ•ฉ๋‹ˆ๋‹ค. ํŠนํžˆ ์‚ฐํ™”์งˆ์†Œ๋Š” ํ˜ˆ๊ด€์„ ์ด์™„์‹œํ‚ค๋Š” ํšจ๊ณผ๋ฅผ ํ†ตํ•ด ํ˜ˆ๋ฅ˜๋ฅผ ๊ฐœ์„ ํ•ฉ๋‹ˆ๋‹ค.[1]

L-์•„๋ฅด๊ธฐ๋‹Œ ๋ณด์ถฉ์ œ๋Š” ์‹ฌ์žฅ ๋ฐ ํ˜ˆ๊ด€ ๊ฑด๊ฐ•์„ ๋•๋Š” ์Šคํฌ์ธ  ์˜์–‘ ๋ณด์ถฉ์ œ๋กœ ์‚ฌ์šฉํ•˜๋Š” ๊ฒฝ์šฐ๊ฐ€ ๋งŽ์Šต๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ 3g ์ด์ƒ์˜ ์šฉ๋Ÿ‰์œผ๋กœ ๋งค์ผ L-์•„๋ฅด๊ธฐ๋‹Œ์„ ๋ณด์ถฉํ•˜๋”๋ผ๋„ ๋‹ค์–‘ํ•œ ํšจ๋Šฅ์„ ์–ป์„ ์ˆ˜ ์žˆ์Œ์„ ์ž…์ฆํ•˜๋Š” ์ผ๊ด€์ ์ธ ์ž„์ƒ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋Š” ์•„์ง ๋‚˜์˜ค์ง€ ์•Š๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

L-์•„๋ฅด๊ธฐ๋‹Œ์ด ํ•จ์œ ๋œ ์‹ํ’ˆ

L-์•„๋ฅด๊ธฐ๋‹Œ์€ ๋‹ค์–‘ํ•œ ๊ฒฌ๊ณผ๋ฅ˜์™€ ์”จ์•—, ์œก๋ฅ˜, ํ•ด์‚ฐ๋ฌผ, ์ฝฉ์— ํ•จ์œ ๋˜์–ด ์žˆ์Šต๋‹ˆ๋‹ค. ์ผ๋ฐ˜์ ์œผ๋กœ ์ธ์ฒด๋Š” ์‹๋‹จ์„ ํ†ตํ•œ L-์•„๋ฅด๊ธฐ๋‹Œ ์„ญ์ทจ๊ฐ€ ๋ถ€์กฑํ•  ๋•Œ ์š”๊ตฌ๋Ÿ‰์„ ์ถฉ์กฑํ•˜๋Š” ๋ฐ ํ•„์š”ํ•œ L-์•„๋ฅด๊ธฐ๋‹Œ์„ ์ƒ์„ฑํ•ฉ๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ์ผ๋ถ€ ๊ฒฝ์šฐ์—๋Š” ์ธ์ฒด์˜ L-์•„๋ฅด๊ธฐ๋‹Œ ์š”๊ตฌ๋Ÿ‰์„ ์ถฉ์กฑํ•˜๊ธฐ ์œ„ํ•ด ๋ณด์ถฉ์ œ๋ฅผ ์‚ฌ์šฉํ•ด์•ผ ํ•  ์ˆ˜๋„ ์žˆ์Šต๋‹ˆ๋‹ค. 

L-์‹œํŠธ๋ฃฐ๋ฆฐ์ด๋ž€?

L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ L-์•„๋ฅด๊ธฐ๋‹Œ์˜ ์ „๊ตฌ์ฒด๋กœ์„œ ๋งค์šฐ ๊ธ์ •์ ์ธ ํšจ๊ณผ๋ฅผ ๋ณด์ด๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค.  L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ ์ฃผ๋กœ ์ˆ˜๋ฐ•์— ๋“ค์–ด ์žˆ๋Š” ๋…ํŠนํ•œ ์•„๋ฏธ๋…ธ์‚ฐ์ž…๋‹ˆ๋‹ค. ์ฒด๋‚ด์—์„œ L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ L-์•„๋ฅด๊ธฐ๋‹Œ์œผ๋กœ ์ „ํ™˜๋ฉ๋‹ˆ๋‹ค.[2-5]

L-์‹œํŠธ๋ฃฐ๋ฆฐ ๋ณด์ถฉ์ œ๋Š” L-์•„๋ฅด๊ธฐ๋‹Œ๊ณผ ๋น„๊ตํ•˜์—ฌ ์ฒด๋‚ด L-์•„๋ฅด๊ธฐ๋‹Œ ์ˆ˜์น˜๋ฅผ ๋” ํšจ์œจ์ ์œผ๋กœ ๋†’์ด๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ์ด ๋•Œ๋ฌธ์— L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ L-์•„๋ฅด๊ธฐ๋‹Œ๋ณด๋‹ค ํ›จ์”ฌ ๋” ํšจ๊ณผ์ ์œผ๋กœ ๊ธ์ •์ ์ธ ์ž„์ƒ ๊ฒฐ๊ณผ๋ฅผ ๋ณด์ž…๋‹ˆ๋‹ค. ์Šคํฌ์ธ  ๋ณด์ถฉ์ œ ์—…๊ณ„์—์„œ L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ L-์•„๋ฅด๊ธฐ๋‹Œ๋ณด๋‹ค ์ธ๊ธฐ๊ฐ€ ๋†’์œผ๋ฉฐ ๋‹ค์–‘ํ•œ ๋ณตํ•ฉ ์ œํ’ˆ์—๋„ ์‚ฌ์šฉ๋˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค.[2-5]

์ฒด๋ ฅ ์ฆ์ง„ ํšจ๋Šฅ

์—ฌ๋Ÿฌ ์‹คํ—˜์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด L-์•„๋ฅด๊ธฐ๋‹Œ ๋ณด์ถฉ์ œ๋Š” ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ์ƒ์„ฑ, ํ˜ˆ๋ฅ˜, ๋ฏธํ† ์ฝ˜๋“œ๋ฆฌ์•„ ๊ธฐ๋Šฅ, ์—๋„ˆ์ง€ ๋Œ€์‚ฌ์— ์˜ํ–ฅ์„ ๋ฏธ์น  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ํšจ๋Šฅ์€ ์šด๋™์„ ์ˆ˜๋ฅผ ๋น„๋กฏํ•œ ๋‹ค์–‘ํ•œ ์‚ฌ๋žŒ์—๊ฒŒ ๋„์›€์ด ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ์ž„์ƒ์‹œํ—˜์—์„œ๋Š” L-์•„๋ฅด๊ธฐ๋‹Œ์„ ๋ณด์ถฉํ•˜๋”๋ผ๋„ ์‹ ์ฒด ๋Šฅ๋ ฅ์„ ๋†’์ด๋Š” ๋ฐ ๊ฑฐ์˜ ๋„์›€์ด ๋˜์ง€ ์•Š๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ์ด์™€๋Š” ๋Œ€์กฐ์ ์œผ๋กœ L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ ๋งŽ์€ ์ด์ค‘๋งน๊ฒ€ ์—ฐ๊ตฌ์—์„œ ๊ธ์ •์ ์ธ ๊ฒฐ๊ณผ๋ฅผ ๋ณด์˜€์Šต๋‹ˆ๋‹ค.[1-5] 

์ด๋Ÿฌํ•œ ์—ฐ๊ตฌ์˜ ๋Œ€๋ถ€๋ถ„์—์„œ๋Š” 2.4-6g์˜ ์ผ๋ฐ˜์ ์ธ ์šฉ๋Ÿ‰์œผ๋กœ L-์‹œํŠธ๋ฃฐ๋ฆฐ์„ ๋ณด์ถฉํ•  ๊ฒฝ์šฐ ๊ณ ๊ฐ•๋„ ์ €ํ•ญ ์šด๋™ ์‹œ ๊ทผ๋ ฅ, ํŒŒ์›Œ, ์ง€๊ตฌ๋ ฅ์ด ๋†’์•„์ง€๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.[2-5] ๊ทผ๋ ฅ ์šด๋™ ์‹œ ์ง€๊ตฌ๋ ฅ์€ ๋” ์ด์ƒ ๋™์ž‘์„ ๋ฐ˜๋ณตํ•  ์ˆ˜ ์—†๋Š” ์‹คํŒจ์ง€์ ์— ๋„๋‹ฌํ•˜๋Š” ๋ฐ ํ•„์š”ํ•œ ๋ฐ˜๋ณต ํšŸ์ˆ˜๋กœ ์ •์˜๋ฉ๋‹ˆ๋‹ค. ๊ทผ๋ ฅ ์šด๋™์„ ํ•  ๋•Œ ๋™์ž‘์„ ๋” ๋ฐ˜๋ณตํ•˜์ง€ ๋ชปํ•  ๋•Œ๊นŒ์ง€ ์šด๋™ํ•˜๋Š” ๊ฒƒ์€ ๊ทผ์œก ์„ฑ์žฅ์„ ์ด‰์ง„ํ•˜๋Š” ์ตœ๊ณ ์˜ ๋ฐฉ๋ฒ•์œผ๋กœ ์ธ์ •๋˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ ์‹คํŒจ์ง€์  ์ „๊นŒ์ง€์˜ ๋ฐ˜๋ณต ํšŸ์ˆ˜๋ฅผ ์ฆ๊ฐ€์‹œํ‚ฌ ์ˆ˜ ์žˆ์–ด ๊ทผ๋ ฅ ์šด๋™์— ํฐ ๋„์›€์ด ๋  ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ์ƒ๊ฐ๋ฉ๋‹ˆ๋‹ค.

๋ชจ๋“  ์Šคํฌ์ธ  ์˜ํ•™ ๊ด€๋ จ ์—ฐ๊ตฌ์—์„œ L-์‹œํŠธ๋ฃฐ๋ฆฐ ๋ณด์ถฉ์ œ์˜ ํšจ๋Šฅ์ด ์ž…์ฆ๋œ ๊ฒƒ์€ ์•„๋‹™๋‹ˆ๋‹ค. ํ•˜์ง€๋งŒ ํ˜„์žฌ๊นŒ์ง€ ๋ฐœํ‘œ๋œ ๋ชจ๋“  ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋ฅผ ๋ถ„์„ํ•œ ์—ฌ๋Ÿฌ ๊ฑด์˜ ๋ฌธํ—Œ ๊ฒ€ํ† ์—์„œ๋Š” L-์‹œํŠธ๋ฃฐ๋ฆฐ ๋ณด์ถฉ์ œ๊ฐ€ ๊ณ ๊ฐ•๋„ ๊ทผ๋ ฅ ๋ฐ ํŒŒ์›Œ ์šด๋™ ๋Šฅ๋ ฅ์„ ํ˜„์ €ํžˆ ๊ฐœ์„ ํ•  ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. [2-5] L-์‹œํŠธ๋ฃฐ๋ฆฐ ๋ณด์ถฉ์ œ๋Š” ์›จ์ดํŠธ ํŠธ๋ ˆ์ด๋‹ ํ›„ ๊ทผ์œกํ†ต์„ ์™„ํ™”ํ•˜๋Š” ๋ฐ๋„ ์–ด๋Š ์ •๋„ ํšจ๊ณผ์ ์ธ ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. [6] ํ•˜์ง€๋งŒ L-์‹œํŠธ๋ฃฐ๋ฆฐ ๋ณด์ถฉ์ œ๋Š” ์œ ์‚ฐ์†Œ ์šด๋™ ์‹œ ์ง€๊ตฌ๋ ฅ์„ ๊ฐœ์„ ํ•˜์ง€๋Š” ๋ชปํ•ฉ๋‹ˆ๋‹ค.[7]

์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ๋ถ„๋น„๋ฅผ ์ด‰์ง„ํ•˜๋Š” ํšจ๊ณผ

L-์•„๋ฅด๊ธฐ๋‹Œ์€ ๋‡Œํ•˜์ˆ˜์ฒด์˜ ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ๋ถ„๋น„๋ฅผ ์ด‰์ง„ํ•˜๋Š” ๋ฐ ๋งŽ์ด ์‚ฌ์šฉํ•ฉ๋‹ˆ๋‹ค. ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ์€ ๊ทผ์œก๊ณผ ๊ณจ๊ฒฉ ์„ฑ์žฅ์„ ์ž๊ทนํ•˜๋Š” ์—ญํ• ์„ ํ•ฉ๋‹ˆ๋‹ค. 

๋ณด๋””๋นŒ๋”๋Š” ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ์˜ ์ž์—ฐ์ ์ธ ์ƒ์„ฑ์„ ๋Š˜๋ฆฌ๊ธฐ ์œ„ํ•ด L-์•„๋ฅด๊ธฐ๋‹Œ ๋ณด์ถฉ์ œ๋ฅผ ์„ญ์ทจํ•˜๋Š” ๊ฒฝ์šฐ๊ฐ€ ๋งŽ์Šต๋‹ˆ๋‹ค. ํŠน์ •ํ•œ ๊ฒฝ์šฐ์— ํ•œํ•ด ์ด๋Ÿฌํ•œ ๊ด€ํ–‰์€ ์–ด๋Š ์ •๋„ ๊ทผ๊ฑฐ๊ฐ€ ์žˆ์–ด ๋ณด์ž…๋‹ˆ๋‹ค. L-์•„๋ฅด๊ธฐ๋‹Œ์ด ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ์ƒ์„ฑ์„ ์ฆ๊ฐ€์‹œํ‚ค๋Š” ํšจ๊ณผ๋Š” ์ž˜ ์•Œ๋ ค์ ธ ์žˆ์Šต๋‹ˆ๋‹ค. ์‹ค์ œ๋กœ L-์•„๋ฅด๊ธฐ๋‹Œ์„ ์ •๋งฅ ์ฃผ์‚ฌ๋กœ ์ฃผ์ž…ํ•œ ํ›„ ํ˜ˆ์•ก ๋‚ด ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ์ˆ˜์น˜๋ฅผ ์ธก์ •ํ•˜๋Š” ๋ฐฉ๋ฒ•์€ ์–ด๋ฆฐ์ด๋‚˜ ์„ฑ์ธ์ด ์ถฉ๋ถ„ํ•œ ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ์„ ๋ถ„๋น„ํ•˜๋Š”์ง€ ์—ฌ๋ถ€๋ฅผ ํ‰๊ฐ€ํ•  ๋•Œ ์‚ฌ์šฉํ•ฉ๋‹ˆ๋‹ค. ์ Š์€ ์„ฑ์ธ ๋‚จ์„ฑ์ด ๋งค์ผ 10g์˜ L-์•„๋ฅด๊ธฐ๋‹Œ์„ ๋ณด์ถฉํ•˜๋ฉด ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ๋ถ„๋น„๊ฐ€ ์•ฝ๊ฐ„ ์ฆ๊ฐ€ํ•˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค.[8] ํ•˜์ง€๋งŒ ๋‚˜์ด๊ฐ€ ๋งŽ์€ ์„ฑ์ธ์€ L-์•„๋ฅด๊ธฐ๋‹Œ ๋ณด์ถฉ์ œ๋ฅผ ์„ญ์ทจํ•˜๋”๋ผ๋„ ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ๋ฐฉ์ถœ์ด ๋Š˜์–ด๋‚˜์ง€ ์•Š๋Š” ๊ฒƒ์œผ๋กœ ๋ณด์ž…๋‹ˆ๋‹ค. ๊ฑด๊ฐ•ํ•œ ๋‚จ์„ฑ์ด ๋งค์ผ 15g์˜ L-์‹œํŠธ๋ฃฐ๋ฆฐ์„ ๋ณด์ถฉํ•œ ๊ฒฝ์šฐ์—๋„ ์„ฑ์žฅ ํ˜ธ๋ฅด๋ชฌ ์ˆ˜์น˜๋Š” ์ฆ๊ฐ€ํ•˜์ง€ ์•Š์•˜์Šต๋‹ˆ๋‹ค.[9]

์‹ฌํ˜ˆ๊ด€๊ณ„ ์ง€์›

์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด L-์•„๋ฅด๊ธฐ๋‹Œ์„ ๋ณด์ถฉํ•˜๋ฉด ์‹ฌ์žฅ ๋ฐ ํ˜ˆ๊ด€ ๊ฑด๊ฐ•์— ๋„์›€์ด ๋˜๋Š” ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. L-์•„๋ฅด๊ธฐ๋‹Œ ๋ณด์ถฉ์ œ๋Š” ์‚ฐํ™”์งˆ์†Œ ์ˆ˜์น˜๋ฅผ ๋†’์—ฌ ํ˜ˆ๋ฅ˜๋ฅผ ๊ฐœ์„ ํ•˜๊ณ  ํ˜ˆ์ „ ์ƒ์„ฑ์„ ์ค„์ด๋ฉฐ ํ˜ˆ์•ก ์œ ๋™์„ฑ์„ ๊ฐœ์„ ํ•ฉ๋‹ˆ๋‹ค(ํ˜ˆ์•ก ๋ฐ€๋„๊ฐ€ ๋‚ฎ์•„์ ธ ํ˜ˆ๊ด€ ๋‚ด ํ๋ฆ„์ด ๋นจ๋ผ์ง).

์ž„์ƒ์‹œํ—˜์— ๋”ฐ๋ฅด๋ฉด ์‹ฌ์žฅ ๋ฐ ํ˜ˆ๊ด€ ๊ฑด๊ฐ•์„ ์ง€์›ํ•˜๋Š” ํšจ๋Šฅ๋„ L-์‹œํŠธ๋ฃฐ๋ฆฐ์ด L-์•„๋ฅด๊ธฐ๋‹Œ๋ณด๋‹ค ์šฐ์ˆ˜ํ•œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ์ด๋Ÿฌํ•œ ์ž„์ƒ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ๋Š” L-์‹œํŠธ๋ฃฐ๋ฆฐ์ด๋‚˜ ์ˆ˜๋ฐ• ์ถ”์ถœ๋ฌผ์ด L-์•„๋ฅด๊ธฐ๋‹Œ๋ณด๋‹ค ํ˜ˆ์••์„ ์กฐ์ ˆํ•˜๋Š” ํšจ๋Šฅ์ด ๋” ์šฐ์ˆ˜ํ•จ์„ ๋ช…๋ฐฑํžˆ ์ž…์ฆํ•˜๋Š” ๊ฒƒ์ž…๋‹ˆ๋‹ค. ๋˜ํ•œ L-์‹œํŠธ๋ฃฐ๋ฆฐ์€ ํ˜ˆ๊ด€๋ฒฝ์˜ ์œ ์—ฐ์„ฑ์„ ํšŒ๋ณตํ•˜๋Š” ํšจ๊ณผ๋„ ๋” ์šฐ์›”ํ•œ ๊ฒƒ์œผ๋กœ ๋ณด์ž…๋‹ˆ๋‹ค.[5]

๋ฐœ๊ธฐ ๊ธฐ๋Šฅ ์ง€์›

์‚ฐํ™”์งˆ์†Œ๋Š” ์Œ๊ฒฝ ๋ฐœ๊ธฐ๋ฅผ ์ผ์œผํ‚ค๋Š” ๋ฐ ํ•„์ˆ˜์ ์ธ ์ƒ๋ฆฌ์  ์‹ ํ˜ธ๋กœ ๊ธฐ๋Šฅํ•ฉ๋‹ˆ๋‹ค. ์ตœ๊ทผ ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์— ๋”ฐ๋ฅด๋ฉด ๋ฐœ๊ธฐ ๋ถ€์ „์ด ์žˆ๋Š” ๋‚จ์„ฑ ์ค‘ ์ƒ๋‹น์ˆ˜๋Š” ๋ฐœ๊ธฐ ๊ธฐ๋Šฅ์ด ์›ํ™œํ•œ ๋‚จ์„ฑ์— ๋น„ํ•ด ํ˜ˆ์ค‘ L-์•„๋ฅด๊ธฐ๋‹Œ ๋ฐ L-์‹œํŠธ๋ฃฐ๋ฆฐ ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์•˜์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ ์ด๋Ÿฌํ•œ ์•„๋ฏธ๋…ธ์‚ฐ์˜ ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์œผ๋ฉด ๋ฐœ๊ธฐ ์กฐ์ง์œผ๋กœ ์œ ์ž…๋˜๋Š” ํ˜ˆ๋ฅ˜๊ฐ€ ๊ฐ์†Œํ•  ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. ๋ฐœ๊ธฐ ๋Šฅ๋ ฅ์ด ์ €ํ•˜๋˜๊ณ  ์Œ๊ฒฝ ํ˜ˆ๋ฅ˜๊ฐ€ ๋ถ€์กฑํ•ด์ง€๋Š” ์ด์œ ๋Š” L-์•„๋ฅด๊ธฐ๋‹Œ ๋ฐ L-์‹œํŠธ๋ฃฐ๋ฆฐ ์ˆ˜์น˜๊ฐ€ ๋‚ฎ์•„ ์‚ฐํ™”์งˆ์†Œ ์ƒ์„ฑ์ด ๊ฐ์†Œํ•˜๊ธฐ ๋•Œ๋ฌธ์ธ ๊ฒƒ์œผ๋กœ ์ƒ๊ฐ๋ฉ๋‹ˆ๋‹ค.[10]

ํ•œ ์ž„์ƒ์‹œํ—˜์—์„œ๋Š” 1๊ฐœ์›” ๋™์•ˆ ๋งค์ผ L-์‹œํŠธ๋ฃฐ๋ฆฐ 1.5g์„ ๋ณด์ถฉํ•œ ๊ฒฝ์šฐ ๋ฐœ๊ธฐ ๊ฐ•์ง๋„ ์ ์ˆ˜๊ฐ€ ํ–ฅ์ƒ๋œ ๊ฒƒ์œผ๋กœ ๋‚˜ํƒ€๋‚ฌ์Šต๋‹ˆ๋‹ค. ์œ„์•ฝ์„ ์„ญ์ทจํ•œ ๋‚จ์„ฑ์˜ ๊ฒฝ์šฐ 8.3%๋งŒ์ด ํ‰๊ท  ๋ฐœ๊ธฐ ๊ฐ•์ง๋„ ์ ์ˆ˜์— ๋„๋‹ฌํ•œ ๋ฐ˜๋ฉด, L-์‹œํŠธ๋ฃฐ๋ฆฐ์„ ๋ณด์ถฉํ•œ ๋‚จ์„ฑ์€ 50%๊ฐ€ ์ด๋Ÿฌํ•œ ์ˆ˜์ค€์„ ๋‹ฌ์„ฑํ–ˆ์Šต๋‹ˆ๋‹ค. L-์‹œํŠธ๋ฃฐ๋ฆฐ์„ ๋ณด์ถฉํ•œ ํ›„ ์›”ํ‰๊ท  ์„ฑ๊ด€๊ณ„ ํšŸ์ˆ˜๋Š” ๊ธฐ์ค€์น˜์ธ 1.37ํšŒ์—์„œ 2.3ํšŒ๋กœ ์ฆ๊ฐ€ํ–ˆ์Šต๋‹ˆ๋‹ค.[11]

L-์•„๋ฅด๊ธฐ๋‹Œ๊ณผ ์†Œ๋‚˜๋ฌด ๊ป์งˆ ์ถ”์ถœ๋ฌผ ๋˜๋Š” L-์‹œํŠธ๋ฃฐ๋ฆฐ๊ณผ ๋ ˆ์Šค๋ฒ ๋ผํŠธ๋กค(Resveratrol)์„ ๋ณ‘์šฉํ•œ ์—ฌ๋Ÿฌ ์ž„์ƒ ์‹œํ—˜์—์„œ๋„ ๊ธ์ •์ ์ธ ๊ฒฐ๊ณผ๊ฐ€ ๋‚˜์™”์Šต๋‹ˆ๋‹ค.[12,13]

์ฐธ๊ณ ๋ฌธํ—Œ:

  1. Gupta MN, Uversky VN. Biological importance of arginine: A comprehensive review of the roles in structure, disorder, and functionality of peptides and proteins. Int J Biol Macromol. 2023 Dec 5:128646.
  2. Rashid J, Kumar SS, Job KM, et al. Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review. Paediatr Drugs. 2020 Jun;22(3):279-293.
  3. Park HY, Kim SW, Seo J, et al. Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review. Nutrients. 2023 Mar 3;15(5):1268. D
  4. Gonzalez AM, Townsend JR, Pinzone AG, Hoffman JR. Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature. Nutrients. 2023 Jan 28;15(3):660.
  5. Trexler ET, Persky AM, Ryan ED,. Acute Effects of Citrulline Supplementation on High-Intensity Strength and Power Performance: A Systematic Review and Meta-Analysis. Sports Med. 2019 May;49(5):707-718. 
  6. Rhim H.C., Kim S.J., Park J., Jang K.-M. Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis. J. Sport Health Sci. 2020;9:553โ€“561.
  7. Viribay A, Fernรกndez-Landa J, Castaรฑeda-Babarro A, et al. Effects of Citrulline Supplementation on Different Aerobic Exercise Performance Outcomes: A Systematic Review and Meta-Analysis. Nutrients. 2022 Aug 24;14(17):3479.
  8. Apolzan JW, Stein JA, Rood JC, et al. Effects of acute arginine supplementation on neuroendocrine, metabolic, cardiovascular, and mood outcomes in younger men: A double-blind, placebo-controlled trial. Nutrition. 2022 Sep;101:111658.
  9. Moinard C, Nicolis I, Neveux N, et al. Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study. Br J Nutr. 2008 Apr;99(4):855-62.
  10. Barassi A, Corsi Romanelli MM, Pezzilli R, et al. Levels of l-arginine and l-citrulline in patients with erectile dysfunction of different etiology. Andrology. 2017 Mar;5(2):256-261.
  11. Cormio L, De Siati M, Lorusso F, et al. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Urology. 2011 Jan;77(1):119-22.
  12. Shirai M, Hiramatsu I, Aoki Y, Shimoyama H, et al. Oral L-citrulline and Transresveratrol Supplementation Improves Erectile Function in Men With Phosphodiesterase 5 Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Study. Sex Med. 2018 Dec;6(4):291-296. 
  13. Tian Y, Zhou Q, Li W, Liu M, Li Q, Chen Q. Efficacy of L-arginine and Pycnogenol ยฎ in the treatment of male erectile dysfunction: a systematic review and meta-analysis. Front Endocrinol (Lausanne). 2023 Oct 4;14:1211720.

๋ฉด์ฑ…์‚ฌํ•ญ:์›ฐ๋‹ˆ์Šค ํ—ˆ๋ธŒ์˜ ์ทจ์ง€๋Š” ์˜ํ•™์ ์ธ ์ง„๋‹จ์ด๋‚˜ ์น˜๋ฃŒ๋ฅผ ์ œ๊ณตํ•˜๋Š” ๊ฒƒ์ด ์•„๋‹™๋‹ˆ๋‹ค. ์ž์„ธํžˆ ์•Œ์•„๋ณด๊ธฐ