์ด ์„ธ์…˜์— ๋Œ€ํ•œ ๊ธฐ๋ณธ ์„ค์ •์ด ์—…๋ฐ์ดํŠธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๊ณ ๊ฐ๋‹˜์˜ ๊ณ„์ • ์„ค์ •์„ ์˜๊ตฌ์ ์œผ๋กœ ๋ณ€๊ฒฝํ•˜๋ ค๋ฉด ๋‚ด ๊ณ„์ •์œผ๋กœ ์ด๋™ํ•˜์„ธ์š”.
์›ํ•˜๋Š” ์ˆ˜๋ น ๊ตญ๊ฐ€ ๋˜๋Š” ์‚ฌ์šฉ ์–ธ์–ด๋ฅผ ๋‚ด ๊ณ„์ •์—์„œ ์–ธ์ œ๋“ ์ง€ ์—…๋ฐ์ดํŠธํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.
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ํฌ๋ฆด์€ ๋Œ€์„œ์–‘์—์„œ ์žกํžˆ๋Š” ์ž‘๊ณ  ๋ถ‰์€ ์ƒ‰์ด๋ฉฐ ๋กญ์Šคํ„ฐ ๊ฐ™์ด ์ƒ๊ธด ์ƒ๋ฌผ์ด๋ฉฐ, ํฌ๋ฆด ์˜ค์ผ์€ ๊ฐ‘๊ฐ๋ฅ˜์—์„œ ์ถ”์ถœ๋˜๋Š” ํ•„์ˆ˜ ์ง€๋ฐฉ์‚ฐ์ž…๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์— ์˜ค๋ฉ”๊ฐ€3 ํ”ผ์‰ฌ ์˜ค์ผ์— ๋“ค์–ด ์žˆ๋Š” ๊ฒƒ๊ณผ ๊ฐ™์€ ์˜ค๋ฉ”๊ฐ€-3 ์ง€๋ฐฉ์‚ฐ์ด ๋“ค์–ด ์žˆ์œผ๋ฏ€๋กœ, ๋งŽ์€ ์‚ฌ๋žŒ๋“ค์ด ์˜ค๋ฉ”๊ฐ€-3 ํ”ผ์‹œ ์˜ค์ผ ๋Œ€์‹  ๋จน์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด์— ๋“ค์–ด ์žˆ๋Š” ์ง€๋ฐฉ์‚ฐ์€ ๋„์ฝ”์‚ฌํ—ฅ์‚ฌ์—๋…ธ์ต ์‚ฐ(DHA)๊ณผ ์—์ด์ฝ”์‚ฌํŽœํƒ€์—๋…ธ์ต ์‚ฐ(EPA)์ž…๋‹ˆ๋‹ค.

ํฌ๋ฆด ์˜ค์ผ์˜ ํšจ๋Šฅ

ํฌ๋ฆด ์˜ค์ผ์„ ๋จน์œผ๋ฉด ์˜ค๋ฉ”๊ฐ€3 ์ง€๋ฐฉ์‚ฐ์˜ ์ˆ˜๋งŽ์€ ๊ฑด๊ฐ• ํšจ๋Šฅ์„ ์ทจํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์„ ๋จน์œผ๋ฉด, CRP, ์ฝœ๋ ˆ์Šคํ…Œ๋กค, ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ, ํ˜ˆ๋‹น์„ ๋ชจ๋‘ ์ค„์ผ ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์ด ์—ฐ๊ตฌ๋กœ ๋ฐํ˜€์กŒ์Šต๋‹ˆ๋‹ค. ๋˜ํ•œ, ํฌ๋ฆด ์˜ค์ผ์€ ์‹ฌ์žฅ๋ณ‘๊ณผ ์•„ํ…Œ๋กฌ์„ฑ ๋™๋งฅ ๊ฒฝํ™”์ฆ ์œ„ํ—˜์„ ์ค„์ผ ์ˆ˜ ์žˆ๋Š” ์ฒœ์—ฐ ํ•ญ์—ผ์ฆ ์•ฝ๋„ ๋ฉ๋‹ˆ๋‹ค. ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ์ด๋‚˜ ๊ณจ๊ด€์ ˆ์—ผ ํ†ต์ฆ๋„ ์ตœ์†Œ๋กœ ์ค„์—ฌ์ค๋‹ˆ๋‹ค. 2016๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด, ํฌ๋ฆด ์˜ค์ผ์ด ๊ฒฐ์žฅ์•” ์„ธํฌ ์„ฑ์žฅ๋„ ์–ต์ œํ•œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค.

CRP(C-๋ฐ˜์‘ ๋‹จ๋ฐฑ์งˆ) ์ค„์ด๊ธฐ

CRP๋Š” ์‹ฌ์žฅ๋ณ‘๊ณผ ๋‡Œ์กธ์ค‘ ์œ„ํ—˜์„ ์ฆ๊ฐ€์‹œํ‚ค๋Š” ์—ผ์ฆ ๋‹จ๋ฐฑ์งˆ์ž…๋‹ˆ๋‹ค. ์šฐ๋ฆฌ ๋ชธ์˜ ๊ณผ๋„ํ•œ ์—ผ์ฆ์€ ๋‹ค๋ฅธ ๋งŽ์€ ์งˆํ™˜๊ณผ ๊ด€๊ณ„๊ฐ€ ์žˆ์Šต๋‹ˆ๋‹ค. American College of Nutrition ์ €๋„์— ์‹ค๋ฆฐ 2007๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด, ํฌ๋ฆด ์˜ค์ผ ์„ญ์ทจ๊ฐ€ CRP ์ˆ˜์ค€ ๋˜๋Š” ์—ผ์ฆ์„ ๊ฑฐ์˜ 20%๋‚˜ ์ค„์—ฌ์ค€๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. Archives of Medical Science ์ €๋„์— ์‹ค๋ฆฐ 2016๋…„ ์—ฐ๊ตฌ๋„ ํ•˜๋ฃจ 2๋ฒˆ 500 mg ํฌ๋ฆด ์˜ค์ผ ์„ญ์ทจ๊ฐ€ CRP๋ฅผ ์ค„์—ฌ์ค€๋‹ค๊ณ  ํ–ˆ์Šต๋‹ˆ๋‹ค. 

์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ ์ •ํ™”

์ด์ œ ๋ˆ„๊ตฌ๋‚˜ ์ฝœ๋ ˆ์Šคํ…Œ๋กค์— ๋Œ€ํ•ด ์–˜๊ธฐํ•˜๊ณ , ์ฝœ๋ ˆ์Šคํ…Œ๋กค์€ ์ข‹์ง€ ์•Š์€ ๊ฒƒ์œผ๋กœ ์ธ์‹ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์‹ค์ œ ์ฝœ๋ ˆ์Šคํ…Œ๋กค์€ ๊ฑด๊ฐ•์— ์•„์ฃผ ์ค‘์š”ํ•œ ์—ญํ• ์„ ํ•ฉ๋‹ˆ๋‹ค. ์ฝœ๋ ˆ์Šคํ…Œ๋กค์€ ์šฐ๋ฆฌ ๋ชธ์—์„œ ์•„์ฃผ ์ค‘์š”ํ•œ ๊ธฐ๋Šฅ์„ ํ•˜๋Š” ์™์Šค ๊ฐ™์€ ๋ฌผ์งˆ์ž…๋‹ˆ๋‹ค. ์šฐ๋ฆฌ ๋ชธ ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ค‘ 20%๋งŒ ์Œ์‹๋ฌผ์„ ํ†ตํ•ด ์„ญ์ทจ๋˜๊ณ  ๋‚˜๋จธ์ง€ 80%๋Š” ๊ฐ„์žฅ์ด ๋งŒ๋“ค์–ด ๋ƒ…๋‹ˆ๋‹ค.

์ฝœ๋ ˆ์Šคํ…Œ๋กค์€ ๋‹ค์Œ์„ ๋งŒ๋“œ๋Š” ๋ฐ ๊ผญ ํ•„์š”ํ•ฉ๋‹ˆ๋‹ค:

  • ๋น„ํƒ€๋ฏผD
  • ๋‚จ์„ฑ ์ฃผ๋œ ํ˜ธ๋ฅด๋ชฌ์ธ ํ…Œ์Šคํ† ์Šคํ…Œ๋ก 
  • ์—ฌ์„ฑ ์ฃผ๋œ ํ˜ธ๋ฅด๋ชฌ์ธ ์—์ŠคํŠธ๋กœ๊ฒ
  • ์‹ ๊ฒฝ ๋ณดํ˜ธ๋ง‰ ์—ญํ• ์„ ํ•˜๋Š” ์‹ ๊ฒฝ ์ฝ”ํŒ…(Myelin sheath)
  • ๊ฐ„์žฅ์ด ๋งŒ๋“œ๋Š” ์ดˆ๋ก์ƒ‰ ๋ฌผ์งˆ๋กœ ์ง€๋ฐฉ์‚ฐ๊ณผ ์ผ๋ถ€ ๋น„ํƒ€๋ฏผ ํก์ˆ˜๋ฅผ ๋•๋Š” ๋‹ด์ฆ™

๊ทธ๋Ÿฌ๋‚˜ ์ด ์ฝœ๋ ˆ์Šคํ…Œ๋กค๊ณผ LDL(๋‚˜์œ) ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๊ฐ€ ์˜ฌ๋ผ๊ฐ€๋ฉด ์‹ฌ์žฅ๋ณ‘๊ณผ ๋‡Œ์กธ์ค‘ ์œ„ํ—˜์ด ์ฆ๊ฐ€ํ•˜๋Š” ๊ฒƒ๋„ ์‚ฌ์‹ค์ด๋ฏ€๋กœ, ์˜์‚ฌ๋“ค์€ ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์ค€์ด ์˜ฌ๋ผ๊ฐ„ ์‚ฌ๋žŒ์—๊ฒŒ ์Šคํƒ€ํ‹ด ๊ณ„ ์•ฝ๋ฌผ ๊ฐ™์€ ์ฝœ๋ ˆ์Šคํ…Œ๋กค ๊ฐ•ํ•˜์ œ(์•„ํ† ๋ฅด๋ฐ”์Šคํƒ€๋‹Œ, ์‹ฌ๋ฐ”์Šคํƒ€ํ‹ด ๋“ฑ)๋ฅผ ์ฒ˜๋ฐฉํ•ด ์ฃผ๋Š” ์ผ์ด ๋งŽ์Šต๋‹ˆ๋‹ค. ์ด๋•Œ ๋งŽ์€ ํ™˜์ž๋“ค์ด ํฌ๋ฆด ์˜ค์ผ(ํ™๊ตญ) ๊ฐ™์€ ๋Œ€์•ˆ์„ ์ฐพ์Šต๋‹ˆ๋‹ค. 

Alternative Medicine Review ์ €๋„์— ์‹ค๋ฆฐ 2004๋…„ ์—ฐ๊ตฌ์—์„œ ํฌ๋ฆด ์˜ค์ผ ์„ญ์ทจ๋กœ ํ˜ˆ์ค‘ ์ด ์ฝœ๋ ˆ์Šคํ…Œ๋กค์„ ๋–จ์–ด๋œจ๋ฆด ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์ด ํ™•์ธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ๋™๋ฌผ ๋Œ€์ƒ 2013๋…„ ์—ฐ๊ตฌ์—์„œ๋„ ํฌ๋ฆด ์˜ค์ผ ์„ญ์ทจ๋กœ ์ด ์ฝœ๋ ˆ์Šคํ…Œ๋กค์„ ๋–จ์–ด๋œจ๋ฆด ์ˆ˜ ์žˆ๋Š” ๊ฒƒ์ด ํ™•์ธ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. 

ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ ์ค„์ด๊ธฐ

ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ๋Š” ํ˜ˆ์ค‘์—์„œ ์ˆœํ™˜ํ•˜๋Š” ์ผ์ข…์˜ ์ง€๋ฐฉ์ž…๋‹ˆ๋‹ค. ์ด์ƒ์ ์ธ ์ˆ˜์ค€์€ 150 mg/dl ์ดํ•˜์ž…๋‹ˆ๋‹ค(๋˜๋Š” 1 liter mmol/L ๋‹น 1.7 millimoles ์ดํ•˜). ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ ์ˆ˜์ค€์ด ์˜ฌ๋ผ๊ฐ€๋ฉด ์‹ฌ์žฅ๋งˆ๋น„๋‚˜ ๋‡Œ์กธ์ค‘ ์œ„ํ—˜๋„ ์˜ฌ๋ผ๊ฐ‘๋‹ˆ๋‹ค. 2014๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด, ํฌ๋ฆด ์˜ค์ผ๋กœ ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ10%๋ฅผ ์ค„์ผ ์ˆ˜ ์žˆ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. Nutrition Reviews ์ €๋„์— ์‹ค๋ฆฐ 662๋ช… ํ™˜์ž ๋Œ€์ƒ 2017๋…„ ํฌ๋ฆด ์˜ค์ผ์— ๋Œ€ํ•œ ์—ฐ๊ตฌ๋„ ๋น„์Šทํ•œ ๊ฒฐ๊ณผ๋ฅผ ๋ƒˆ์Šต๋‹ˆ๋‹ค. ๋‹ค๋ฅธ ์—ฐ๊ตฌ๋“ค๋„ ์ด ๊ฒฐ๊ณผ๋ฅผ ์ง€์ง€ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

๋‚˜์œ ์ฝœ๋ ˆ์Šคํ…Œ๋กค(LDL) ์ค„์ด๊ธฐ

๋‚˜์œ ์ฝœ๋ ˆ์Šคํ…Œ๋กค(LDL)์€ ์‹ฌ์žฅ๋ณ‘์— ๋Œ€ํ•œ ๋Œ€ํ‘œ์ ์ธ ์œ„ํ—˜ ์ธ์ˆ˜์ž…๋‹ˆ๋‹ค. ํŠนํžˆ ์‚ฐํ™”๋œ LDL์ด ๋ฌธ์ œ์ธ ๊ฒƒ ๊ฐ™์Šต๋‹ˆ๋‹ค. ์˜์‚ฌ๋“ค์ด ์ฒ˜๋ฐฉํ•ด์ฃผ๋Š” ์ฝœ๋ ˆ์Šคํ…Œ๋กค ๊ฐ•ํ•˜์ œ๋Š” ๋‚˜์œ ์ฝœ๋ ˆ์Šคํ…Œ๋กค(LDL)์„ ๋‚ด๋ ค์ฃผ๋Š” ๊ฒƒ์ž…๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์€ ์ด์— ๋Œ€ํ•œ ์ฒœ์—ฐ ๋ฌผ์งˆ ์˜ต์…˜์ž…๋‹ˆ๋‹ค. Nutrition Reviews ์ €๋„์— ์‹ค๋ฆฐ 662๋ช… ํ™˜์ž ๋Œ€์ƒ 2017๋…„ ํฌ๋ฆด ์˜ค์ผ์— ๋Œ€ํ•œ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ ์„ญ์ทจ๋กœ LDL์„ ์ค„์ผ ์ˆ˜ ์žˆ๋‹ค๋Š” ๊ฒฐ๊ณผ๋ฅผ ๋ƒˆ์Šต๋‹ˆ๋‹ค. ๋‹ค๋ฅธ ์—ฐ๊ตฌ๋“ค๋„ ์ด ๊ฒฐ๊ณผ๋ฅผ ์ง€์ง€ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

ํ˜ˆ๋‹น ์ˆ˜์ค€ ๋‚ด๋ฆฌ๊ธฐ ๊ฐ€๋Šฅ์„ฑ

์„ธ๊ณ„๋ณด๊ฑด๊ธฐ๊ตฌ WHO์— ์˜ํ•˜๋ฉด ์ „ ์„ธ๊ณ„์— ๋‹น๋‡จ๋ณ‘ ํ™˜์ž๊ฐ€ 4์–ต2์ฒœ2๋ฐฑ๋งŒ ๋ช… ์žˆ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ๋‹น๋‡จ๋ณ‘์€ ์ฝฉํŒฅ ์งˆํ™˜, ์‹ฌ์žฅ๋งˆ๋น„, ๋‡Œ์กธ์ค‘์˜ ๋Œ€ํ‘œ์  ์œ„ํ—˜ ์ธ์ˆ˜์ž…๋‹ˆ๋‹ค. ๋‹น๋‡จ๋ณ‘ ์ง„ํ–‰์„ ๋˜๋Œ๋ฆฌ๊ฑฐ๋‚˜ ๊ด€๋ฆฌํ•˜๋ ค๋ฉด, ๋‹ค์ด์–ดํŠธ์™€ ๋ผ์ดํ”„์Šคํƒ€์ผ์ด ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. Alternative Medicine Review ์ €๋„์— ์‹ค๋ฆฐ 2004๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์ด ํ˜ˆ๋‹น(๊ธ€๋ฃจ์ฝ”์Šค)์„ ์ค„์ธ๋‹ค๊ณ  ํ–ˆ๊ณ , British Medical Journal ์ €๋„์— ์‹ค๋ฆฐ 2015๋…„ ์—ฐ๊ตฌ๋Š” ํ•˜๋ฃจ์— ํฌ๋ฆด ์˜ค์ผ 1.000 mg์„ญ์ทจ๋กœ ๊ธ€๋ฃจ์ฝ”์Šค ๋ฏผ๊ฐ์„ฑ์„ ์˜ฌ๋ ค์„œ ์ธ์Š๋ฆฐ์„ ๋” ํšจ๊ณผ์ ์œผ๋กœ ๋งŒ๋“ค์–ด์ง€๊ฒŒ ํ•  ์ˆ˜ ์žˆ๋‹ค๊ณ  ํ–ˆ์Šต๋‹ˆ๋‹ค. ํ˜„์žฌ ์ถ”๊ฐ€ ์—ฐ๊ตฌ๋“ค์ด ์ง„ํ–‰ ์ค‘์ž…๋‹ˆ๋‹ค. 

์ข‹์€ ์žฅ ๋ฐ•ํ…Œ๋ฆฌ์•„ ๋Š˜์ด๊ธฐ

ํฌ๋ฆด ์˜ค์ผ์€ ์žฅ์—์„œ ์‚ฌ๋Š” ๋ฐ•ํ…Œ๋ฆฌ์•„๋“ค์—๊ฒŒ ์•„์ฃผ ์ข‹์€ ๋จน์ด๋กœ์„œ ์ข‹์€ ์ฐฝ์ž ๋ฐ•ํ…Œ๋ฆฌ์•„๋ฅผ ๋Š˜๋ฆด ์ˆ˜ ์žˆ๋Š” ํ”„๋กœ๋ฐ”์ด์˜คํ‹ฑ์ž…๋‹ˆ๋‹ค. ์žฅ ๊ฑด๊ฐ•์—๋Š” ์œ ์‚ฐ๊ท ์ด๋‚˜ ๋น„ํ”ผ๋”์Šค๊ท  ๊ฐ™์€ ๊ท ๋ฅ˜๊ฐ€ ์ค‘์š”ํ•œ๋ฐ, ํฌ๋ฆด ์˜ค์ผ์€ ์ข‹์€ ๋ฐ•ํ…Œ๋ฆฌ์•„๋Š” ํ‚ค์šฐ๊ณ  ๋‚˜์œ ๋ฐ•ํ…Œ๋ฆฌ์•„๋Š” ์–ต์ œํ•ฉ๋‹ˆ๋‹ค. ์žฅ๋ฒฝ์ด ๊ฑด๊ฐ•ํ•˜๋ฉด, ์ˆ˜๋งŽ์€ ๊ฑด๊ฐ• ๋ฌธ์ œ๋ฅผ ์ผ์œผํ‚ค๋Š” ์žฅ ๋ˆ„์ˆ˜๊ฐ€ ์ƒ๊ธฐ์ง€ ์•Š์Šต๋‹ˆ๋‹ค.  ์žฅ ๋ˆ„์ˆ˜ ์ฆํ›„๊ตฐ์— ๋Œ€ํ•ด ๋” ์•Œ์•„๋ณด๊ธฐ

์ƒ์‹๋ ฅ

๋งŽ์€ ๋ถ€๋ถ€๋“ค์ด ๋ถˆ์ž„ ๋ฌธ์ œ๋กœ ๊ณ ๋ฏผํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ์ •์ž ์ˆ˜๊ฐ€ ์ ๊ฑฐ๋‚˜ ์ •์ž ํ’ˆ์งˆ์ด ๋‚˜์œ ๊ฒƒ์ด ๋ณดํ†ต ๋ถˆ์ž„์˜ ์›์ธ์ž…๋‹ˆ๋‹ค. ๋ถˆ์ž„ ์น˜๋ฃŒ๋ฅผ ์ „๋ฌธ๊ฐ€์—๊ฒŒ ๋ฐ›๋Š” ๋ฐ๋Š” ์ˆ˜๋งŒ ๋‹ฌ๋Ÿฌ ์ด์ƒ ๋น„์šฉ์ด ๋“ญ๋‹ˆ๋‹ค. Andrology ์ €๋„์— ์‹ค๋ฆฐ 2017๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์ด ์ •์ž ๊ฐœ์ฒด ์ˆ˜์™€ ํ™œ๋™ ํŒŒ์›Œ๋ฅผ ์˜ฌ๋ฆด ์ˆ˜ ์žˆ๋‹ค๊ณ  ํ–ˆ์Šต๋‹ˆ๋‹ค. ๋ถˆ์ž„ ์น˜๋ฃŒ๋ฅผ ๋ฐ›๊ธฐ ์ „ ์‹œ๋„ํ•ด ๋ณผ ๋งŒํ•œ ๊ฒฝ์ œ์ ์ธ ์˜ต์…˜์ž…๋‹ˆ๋‹ค.

์ฒด์ค‘ ๊ฐ๋Ÿ‰

๊ณผ์ฒด์ค‘์€ ์ „ ์„ธ๊ณ„์  ๊ฑด๊ฐ• ์ด์Šˆ์ž…๋‹ˆ๋‹ค. ๋ฏธ๊ตญ์˜ ๊ฒฝ์šฐ 3๋ช… ์ค‘ 2๋ช… ์ฆ‰ 2์–ต ์ฒœ5๋ฐฑ๋งŒ ๋ช…์ด ๊ณผ์ฒด์ค‘ ๋˜๋Š” ๋น„๋งŒ์ž…๋‹ˆ๋‹ค. ์ค‘๊ตญ, ๋Ÿฌ์‹œ์•„, ์œ ๋Ÿฝ์—์„œ๋„ ๋น„๋งŒ์€ ๋ฌธ์ œ๋กœ ๋– ์˜ค๋ฅด๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ๋น„๋งŒ์€ ๋‹น๋‡จ, ์‹ฌ์žฅ๋ณ‘, ๋‡Œ์กธ์ค‘ ๋“ฑ ์—ฌ๋Ÿฌ ์งˆํ™˜ ์œ„ํ—˜์„ ์ฆ๊ฐ€์‹œํ‚ต๋‹ˆ๋‹ค. ๊ท ํ˜• ์žกํžŒ ๋‹ค์ด์–ดํŠธ์™€ ๊ทœ์น™์ ์ธ ์šด๋™์ด ๊ฑด๊ฐ•ํ•œ ์ฒด์ค‘ ์œ ์ง€์— ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. ๋ณด์ถฉ์ œ๋„ ๋„์›€์ด ๋˜๋Š” ๊ฒฝ์šฐ๊ฐ€ ์žˆ์Šต๋‹ˆ๋‹ค. PLOS ์ €๋„์— ์‹ค๋ฆฐ 2017๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์ด ๋น„๋งŒํ•œ ์‹คํ—˜์šฉ ์ฅ ์ฒด์ค‘์„ ์ค„์˜€๋Š”๋ฐ, ์•„๋งˆ๋„ ํฌ๋ฆด ์˜ค์ผ์ด ์ฐฝ์ž์˜ ๋ฏธ์ƒ๋ฌผ ๊ตฐ์ง‘์„ ๋ณ€ํ™”์‹œ์ผœ ๋Œ€์‚ฌ๋Ÿ‰์„ ์ฆ๊ฐ€์‹œํ‚ค๋Š” ๊ฒƒ์ด ์›์ธ ๊ฐ™๋‹ค๊ณ  ๋ณด๊ณ ํ–ˆ์Šต๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์ธ๊ฐ„ ๋Œ€์ƒ ์—ฐ๊ตฌ๊ฐ€ ์•„์ง ๋” ํ•„์š”ํ•ฉ๋‹ˆ๋‹ค.

๊ธฐ์–ต๋ ฅ ๊ฐœ์„ 

์•Œ์ธ ํ•˜์ด๋จธ ๋ณ‘์€ ๋ฏธ๊ตญ์—์„œ ์‚ฌ๋ง์— ์ด๋ฅด๋Š” ๋ณ‘ ์ œ3์œ„๊ณ , ๋งŽ์€ ์˜์‚ฌ๋“ค์ด ์น˜๋งค์˜ ๊ฐ€์žฅ ํ”ํ•œ ํ˜•ํƒœ๊ฐ€ ์•Œ์ธ ํ•˜์ด๋จธ ๋ณ‘์ด๋ผ๊ณ  ๋ณด๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์ด ์ธ์ง€ ๋Šฅ๋ ฅ ์ˆ˜์ค€์„ ์œ ์ง€ํ•˜๋Š” ๋ฐ ๋„์›€์ด ๋œ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. Food and Function ์ €๋„์— ์‹ค๋ฆฐ 2017๋…„ ๋™๋ฌผ ๋Œ€์ƒ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์ด ์ธ์ง€ ๊ธฐ๋Šฅ์„ ์ข‹์•„์ง€๊ฒŒ ํ•œ๋‹ค๊ณ  ํ–ˆ์Šต๋‹ˆ๋‹ค. Clinical Interventions in Aging ์ €๋„์— ์‹ค๋ฆฐ 2013๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์„ ๋จน์€ ๋…ธ์ธ๋“ค์˜ ์ธ์ง€ ๊ธฐ๋Šฅ์ด ๊ฐœ์„ ๋˜์—ˆ๋‹ค๊ณ  ํ–ˆ์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ๊ณผ ๊ฐ™์ด ๋จน์œผ๋ฉด ๊ธฐ์–ต๋ ฅ์„ ๊ฐœ์„ ํ•  ์ˆ˜ ์žˆ๋Š” ๋ณด์ถฉ์ œ๋“ค์ด ๋ช‡ ๊ฐœ ์žˆ์Šต๋‹ˆ๋‹ค. ๊ธฐ์–ต๋ ฅ ๊ฐœ์„ ์— ๋Œ€ํ•ด ๋” ์•Œ์•„๋ณด์„ธ์š”.

๊ฑด์กฐํ•œ ๋ˆˆ

๋‚˜์ด๋ฅผ ๋จน์œผ๋ฉด ๋ˆˆ๋ฌผ์„ ๋งŒ๋“ค์–ด ๋ˆˆ์„ ์ด‰์ด‰ํ•˜๊ฒŒ ํ•˜๋Š” ๋ˆˆ๋ฌผ ๊ธธ ํšจ์œจ์ด ๋‚˜๋น ์ง‘๋‹ˆ๋‹ค. ๊ทธ๋ ‡๊ฒŒ ๋˜๋ฉด ์‹œ์•ผ๊ฐ€ ํ๋ ค์ง€๊ณ , ๋ˆˆ์ด ์ถฉํ˜ˆ๋˜๋ฉฐ, ๋ญ”๊ฐ€ ๋ˆˆ ์†์— ๋“ค์–ด์žˆ๋Š” ๊ฒƒ ๊ฐ™์€ ๋Š๋‚Œ์ด ์˜ต๋‹ˆ๋‹ค. ๊ฑด์กฐํ•œ ๋ˆˆ ๋•Œ๋ฌธ์— ๋งค๋…„ ์ˆ˜๋ฐฑ๋งŒ ๋ช…์ด ์•ˆ๊ณผ๋ฅผ ์ฐพ์Šต๋‹ˆ๋‹ค. Ophthalmology ์ €๋„์— ์‹ค๋ฆฐ 2017๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ ๋ณด์ถฉ์ œ๋ฅผ ๋จน์—ˆ๋”๋‹ˆ ๊ฑด์กฐํ•œ ๋ˆˆ์ด ๊ฐœ์„ ๋˜์—ˆ๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ๋˜ ๋‹ค๋ฅธ 2017๋…„ ์—ฐ๊ตฌ๋„ ํฌ๋ฆด ์˜ค์ผ์„ ํ•˜๋ฃจ 1,500 mg ๋จน์—ˆ๋”๋‹ˆ ๊ฑด์กฐํ•œ ๋ˆˆ์ด ๊ฐœ์„ ๋˜๊ณ  ์‚ฐํ™”๋กœ๋ถ€ํ„ฐ ๋ˆˆ์ด ๋ณดํ˜ธ๋˜์—ˆ๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ ์—ผ์ฆ ์ค„์ด๊ธฐ

๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ์€ ๋ชธ ๋ฉด์—ญ ์‹œ์Šคํ…œ์ด ๊ด€์ ˆ ๋ผ์ด๋‹์„ ๊ณต๊ฒฉํ•˜๋Š” ์ž๊ธฐ ๋ฉด์—ญ ์ƒํƒœ์˜ ๊ฒฐ๊ณผ์ž…๋‹ˆ๋‹ค. ์ด๋ ‡๊ฒŒ ๋˜๋ฉด ์—ฐ๊ณจ์ด ํŒŒ๊ดด๋ฉ๋‹ˆ๋‹ค. ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ์€ ์–ด๋Š ๋‚˜์ด ๋Œ€๋ผ๋„ ์ผ์–ด๋‚  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์•„์นจ์— ๊ด€์ ˆ์ด ๊ตณ์–ด ์žˆ๊ณ  ๊ทธ ์ƒํƒœ๊ฐ€ 1 ์‹œ๊ฐ„ ๋˜๋Š” ํ•˜๋ฃจ ์ข…์ผ ๊ณ„์†๋˜๋Š” ํ˜„์ƒ์ด ๋ช‡ ์ฃผ ๋˜๋Š” ๋ช‡ ๋‹ฌ ๊ณ„์†๋˜๋ฉด, ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ์ž…๋‹ˆ๋‹ค. ๋งŽ์€ ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ ํ™˜์ž๋“ค์€ ์†Œํ™” ์žฅ์• ๋„ ๊ฐ™์ด ๊ฒช๊ณ  ์žˆ์œผ๋ฉฐ ํ•ญ์ƒ ํ”ผ๋กœํ•˜๊ณ  ๋ชธ์ด ์•ˆ ์ข‹์Šต๋‹ˆ๋‹ค. 

์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด, ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ ํ™˜์ž 60%๊ฐ€ ๋ณด์ถฉ์ œ ๋˜๋Š” ๋Œ€์•ˆ ์•ฝ์ œ๋ฅผ ๋จน์–ด๋ณด์•˜๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ๋„ ๊ทธ ์ค‘ ํ•˜๋‚˜์ž…๋‹ˆ๋‹ค. ๊ด€์ ˆ์—ผ, ์ฒœ์—ฐ ํ†ต์ฆ ๊ด€๋ฆฌ ์— ๋Œ€ํ•œ ๋‹ค๋ฅธ ์˜ต์…˜์„ ์•Œ์•„๋ณด์‹ญ์‹œ์˜ค. 

2010๋…„ ์—ฐ๊ตฌ์— ๋”ฐ๋ฅด๋ฉด, ํฌ๋ฆด ์˜ค์ผ์ด ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ ์—ผ์ฆ์„ ์™„ํ™”์‹œํ‚จ๋‹ค๊ณ  ํ•ฉ๋‹ˆ๋‹ค. BMC Musculoskeletal ์ €๋„์— ์‹ค๋ฆฐ 2010๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์ด ๋ฅ˜๋จธํ‹ฐ์ฆ˜์„ฑ ๊ด€์ ˆ์—ผ ๋ฐœ์ƒ ์ž์ฒด๋ฅผ ๋ง‰๋Š” ๋ฐ ๋„์›€์ด ๋˜์—ˆ๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค.

๊ณจ๊ด€์ ˆ์—ผ

๊ณจ๊ด€์ ˆ์—ผ์€ ๋ณดํ†ต ๊ด€์ ˆ์˜ โ€œ๋งˆ๋ชจ์™€ ์ฐข๊น€โ€ ๋•Œ๋ฌธ์— ์ƒ๊น๋‹ˆ๋‹ค. ๋ผˆ๋ฅผ ๋ฎ๊ณ  ์žˆ๋Š” ์ฟ ์…˜ ์—ญํ• ์„ ํ•˜๋Š” ์—ฐ๊ณจ ํŒŒ๊ดด๊ฐ€ ์›์ธ์ž…๋‹ˆ๋‹ค. 40์„ธ๊ฐ€ ๋„˜์œผ๋ฉด ๊ณจ๊ด€์ ˆ์—ผ์ด ์ƒ๊ธธ ์ˆ˜ ์žˆ์œผ๋ฉฐ, ๋‚˜์ด๋ฅผ ๋จน์–ด๊ฐ€๋ฉด์„œ ์ง„ํ–‰๋ฉ๋‹ˆ๋‹ค. 60์„ธ ์ด์ƒ ๋…ธ์ธ์€ ๊ฑฐ์˜ ๋ชจ๋‘ ๊ณจ๊ด€์ ˆ์—ผ์ด ์žˆ์Šต๋‹ˆ๋‹ค. 

๊ด€์ ˆ์—ผ์˜ ์ฆ์ƒ:  

  • ๊ด€์ ˆ ํ†ต์ฆ 
  • ๊ด€์ ˆ ๋ถ€์–ด ์˜ค๋ฆ„ 
  • ๊ด€์ ˆ์ด ๊ตณ์Œ 
  • ๊ด€์ ˆ ๋ณ€ํ˜• 
  • ๊ด€์ ˆ ๊ธฐ๋Šฅ ์ƒ์‹ค

American Journal of Clinical Nutrition ์ €๋„์— ์‹ค๋ฆฐ 2007๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ 300mg ์„ญ์ทจ๊ฐ€ โ€œ์„ญ์ทจ ํ›„ 7์ผ์—์„œ 14์ผ"์ด๋ผ๋Š” ์งง์€ ๊ธฐ๊ฐ„์— ๊ด€์ ˆ์—ผ ์ฆ์ƒ์„ ์™„ํ™”ํ•˜๊ณ  ์—ผ์ฆ์„ ์ƒ๋‹นํžˆ ์ฐจ๋‹จโ€ํ–ˆ๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ์‹ฌํ•˜์ง€ ์•Š์€ ๋ฌด๋ฆŽ ๊ด€์ ˆ ํ†ต์ฆ์ด ์žˆ๋Š” ํ™˜์ž๋“ค์„ ๋Œ€์ƒ์œผ๋กœ 2016๋…„์— ํ–‰ํ•ด์ง„ ์ด์ค‘ ๋ธ”๋ผ์ธ๋“œ ํ”Œ๋ผ์„ธ๋ณด ์‚ฌ์šฉ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ ํ•˜๋ฃจ 2,000 mg ์„ญ์ทจ๋กœ  ๊ด€์ ˆํ†ต์ด ์™„ํ™”๋˜์—ˆ๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

๋ถ€์ž‘์šฉ

๋งŽ์€ ์˜์‚ฌ๋“ค์€ ์™€ํŒŒ๋ฆฐ(์ฟ ๋งˆ๋”˜) ๊ฐ™์€ ํ˜ˆ์•กํฌ์„์ œ๋ฅผ ๋จน๋Š” ํ™˜์ž๋“ค์—๊ฒŒ ํฌ๋ฆด ์˜ค์ผ์„ ๋จน์ง€ ๋ง๋ผ๊ณ  ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ๊ทธ ์ด์œ ๋Š” ์ถœํ˜ˆ ์œ„ํ—˜์ด ์ฆ๊ฐ€๋˜๊ธฐ ๋•Œ๋ฌธ์ž…๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์ด ์šฐ๋ ค๋Š” ๊ทผ๊ฑฐ๊ฐ€ ์—†๋Š” ๊ฒƒ ๊ฐ™์Šต๋‹ˆ๋‹ค. Nutrients ์ €๋„์— ์‹ค๋ฆฐ 2016๋…„ ์—ฐ๊ตฌ๋Š” ํฌ๋ฆด ์˜ค์ผ์„ ํ˜ˆ์•กํฌ์„์ œ์™€ ๊ฐ™์ด ๋จน์–ด๋„ ์ถœํ˜ˆ ์œ„ํ—˜์ด ์ฆ๊ฐ€ํ•˜์ง€ ์•Š์•˜๋‹ค๊ณ  ๋ณด๊ณ ํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ๊ทธ๋Ÿฌ๋‚˜ ์ž„์‹ ๋ถ€๋Š” ํฌ๋ฆด ์˜ค์ผ ๋ณด์ถฉ์ œ ์„ญ์ทจ ์ „์— ์˜์‚ฌ์™€ ์ƒ์˜ํ•˜๋Š” ๊ฒƒ์ด ์ข‹์Šต๋‹ˆ๋‹ค. 

๊ถŒ์žฅ ์„ญ์ทจ๋Ÿ‰

ํฌ๋ฆด ์˜ค์ผ ๊ถŒ์žฅ ์„ญ์ทจ๋Ÿ‰์€ ๋ณดํ†ต ํ•˜๋ฃจ 500mg ~ 2,000mg ์ž…๋‹ˆ๋‹ค.  ๋ช‡๋ช‡ ๋ณด์ถฉ์ œ ์ œ์กฐ์‚ฌ๋Š” ํ•ญ์—ผ์ฆ ํšจ๊ณผ๊ฐ€ ๋” ํฌ๊ณ  ํ•ญ์‚ฐํ™” ๊ฑด๊ฐ• ํ˜œํƒ์„ ์ทจํ•˜๋„๋ก ํฌ๋ฆด ์˜ค์ผ์„ ์•„์Šคํƒ€์ž”ํ‹ด๊ณผ ๊ฒฐํ•ฉํ•œ ๋ณด์ถฉ์ œ๋ฅผ ํŒ๋งคํ•˜๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. 

์š”์•ฝ

ํฌ๋ฆด ์˜ค์ผ์€ ์•„์ฃผ ๋งŽ์€ ๊ฑด๊ฐ• ํšจ๋Šฅ์ด ์žˆ์œผ๋ฏ€๋กœ ๋งŽ์€ ์‚ฌ๋žŒ๋“ค์ด ์˜ค๋ฉ”๊ฐ€3 ํ”ผ์‰ฌ ์˜ค์ผ ๋Œ€์‹  ๋จน๊ณ  ์žˆ์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์€ ํšจ๋Šฅ๋„ ๋” ์ข‹์•„์„œ ๋” ํฐ ์˜ค๋ฉ”๊ฐ€3 ํ”ผ์‰ฌ ์˜ค์ผ ์„ญ์ทจ๋Ÿ‰๋งŒํผ ํšจ๊ณผ๊ฐ€ ์žˆ๋Š” ๊ฒƒ์œผ๋กœ ๋ณด์ž…๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์„ CRP ์—ผ์ฆ ์™„ํ™”๋‚˜ ์ฝœ๋ ˆ์Šคํ…Œ๋กค ๋˜๋Š” ํŠธ๋ฆฌ๊ธ€๋ฆฌ์„ธ๋ผ์ด๋“œ ๊ฐ•ํ•˜์ œ ๋Œ€์‹  ๋จน๋Š” ๊ฒฝ์šฐ๋„ ๋งŽ์Šต๋‹ˆ๋‹ค. ํฌ๋ฆด ์˜ค์ผ์„ ๊ด€์ ˆ์—ผ ๊ด€๋ จ ํ†ต์ฆ ์™„ํ™” ๋˜๋Š” ๊ฑด์กฐํ•œ ๋ˆˆ๊ณผ ํ”ผ๋ถ€ ๊ฐœ์„ ์„ ์œ„ํ•ด ๋จน๊ธฐ๋„ ํ•ฉ๋‹ˆ๋‹ค. ํ˜ˆ์•กํฌ์„์ œ๋ฅผ ๋ณต์šฉํ•˜๊ณ  ์žˆ๋Š” ์ค‘์ด๋ผ๋ฉด ํฌ๋ฆด ์˜ค์ผ ๋ณด์ถฉ์ œ๋ฅผ ์„ญ์ทจํ•˜๊ธฐ ์ „์— ๋จผ์ € ์˜์‚ฌ์™€ ์ƒ์˜ํ•˜์‹ญ์‹œ์˜ค. ๋งˆ์ง€๋ง‰์œผ๋กœ, ๋ณด์ถฉ์ œ๊ฐ€ ๊ณผ์ผ์ด๋‚˜ ์•ผ์ฑ„๊ฐ€ ํ’๋ถ€ํ•œ ๊ฑด๊ฐ•ํ•˜๊ณ  ๊ท ํ˜• ์žกํžŒ ๋‹ค์ด์–ดํŠธ๋ฅผ ๋Œ€์‹ ํ•  ์ˆ˜๋Š” ์—†๋‹ค๋Š” ๊ฒƒ์„ ๋ง๋ถ™์ž…๋‹ˆ๋‹ค.

์ฐธ๊ณ  ๋ฌธํ—Œ:

  1. Mol Nutr Food Res. 2017 Aug 15. doi: 10.1002/mnfr.201700098. [Epub ahead of print]- Krill oil can help  prevent atherosclerosis
  2. Jayathilake AG, Senior PV, Su XQ. Krill oil extract suppresses cell growth and induces apoptosis of human colorectal cancer cells. BMC Complementary and Alternative Medicine. 2016;16(1):328. doi:10.1186/s12906-016-1311-x.
  3. J Am Coll Nutr. 2007 Feb;26(1):39-48.
  4. Cicero AFG, Rosticci M, Morbini M, et al. Lipid-lowering and anti-inflammatory effects of omega 3 ethyl esters and krill oil: a randomized, cross-over, clinical trial. Archives of Medical Science : AMS. 2016;12(3):507-512. doi:10.5114/aoms.2016.59923.
  5. 80% of cholesterol is made in the liver , accessed October 31st, 2017. https://www.health.harvard.edu/heart-health/how-its-made-cholesterol-production-in-your-body
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  7. Li, D.-M., Zhou, D.-Y., Zhu, B.-W., Chi, Y.-L., Sun, L.-M., Dong, X.-P., Qin, L., Qiao, W.-Z. and Murata, Y. (2013), Effects of krill oil intake on plasma cholesterol and glucose levels in rats fed a high-cholesterol diet. J. Sci. Food Agric., 93: 2669โ€“2675. doi:10.1002/jsfa.6072
  8. Nutr Res. 2014 Feb;34(2):126-33. doi: 10.1016/j.nutres.2013.12.003. Epub 2013 Dec 18.
  9. Sorin Ursoniu, Amirhossein Sahebkar, Maria-Corina Serban, Diana Antal, Dimitri P. Mikhailidis, Arrigo Cicero, Vasilios Athyros, Manfredi Rizzo, Jacek Rysz, Maciej Banach, for the Lipid and Blood Pressure Meta-analysis Collaboration Group; Lipid-modifying effects of krill oil in humans: systematic review and meta-analysis of randomized controlled trials, Nutrition Reviews, Volume 75, Issue 5, 1 May 2017, Pages 361โ€“373, https://doi.org/10.1093/nutrit/nuw063
  10. Sorin Ursoniu, Amirhossein Sahebkar, Maria-Corina Serban, Diana Antal, Dimitri P. Mikhailidis, Arrigo Cicero, Vasilios Athyros, Manfredi Rizzo, Jacek Rysz, Maciej Banach, for the Lipid and Blood Pressure Meta-analysis Collaboration Group; Lipid-modifying effects of krill oil in humans: systematic review and meta-analysis of randomized controlled trials, Nutrition Reviews, Volume 75, Issue 5, 1 May 2017, Pages 361โ€“373, https://doi.org/10.1093/nutrit/nuw063
  11. (Altern Med Rev 2004;9(4):420-428
  12. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Research & Care. 2015;3(1):e000107. doi:10.1136/bmjdrc-2015-000107.
  13. Andrology. 2017 May;5(3):423-430. doi: 10.1111/andr.12348. Epub 2017 Mar 23.
  14. PLoS One. 2017 Oct 9;12(10):e0186216. doi: 10.1371/journal.pone.0186216. eCollection 2017.
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  16. Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clinical Interventions in Aging. 2013;8:1247-1257. doi:10.2147/CIA.S50349.
  17. Deinema LA, Vingrys AJ, Wong CY, et. al.  A Randomized, Double-Masked, Placebo-Controlled Clinical Trial of Two Forms of Omega-3 Supplements for Treating Dry Eye Disease.  Ophthalmology. 2017 Jan;124(1):43-52. doi: 10.1016/j.ophtha.2016.09.023. Epub 2016 Nov 3.
  18. Ierna M, Kerr A, Scales H, Berge K, Griinari M. Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskeletal Disorders. 2010;11:136. doi:10.1186/1471-2474-11-136.
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  20. Journal of the American College of Nutrition. 2007 Feb;26(1):39-48.
  21. Suzuki Y, Fukushima M, Sakuraba K, Sawaki K, Sekigawa K. Krill oil Improves Mild Knee Joint Pain: A Randomized Control Trial. Gagnier JJ, ed. PLoS ONE. 2016;11(10):e0162769. doi:10.1371/journal.pone.0162769.
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๋ฉด์ฑ…์‚ฌํ•ญ:์›ฐ๋‹ˆ์Šค ํ—ˆ๋ธŒ์˜ ์ทจ์ง€๋Š” ์˜ํ•™์ ์ธ ์ง„๋‹จ์ด๋‚˜ ์น˜๋ฃŒ๋ฅผ ์ œ๊ณตํ•˜๋Š” ๊ฒƒ์ด ์•„๋‹™๋‹ˆ๋‹ค. ์ž์„ธํžˆ ์•Œ์•„๋ณด๊ธฐ